… -negatives, particularly extended spectrum β-lactamases expressing bacteria, increases
the … From a clinical perspective, fast detection of resistant pathogens would allow a pre-emptive …

… well as the decision of narrow versus broad spectrum activity. For empirical therapy, to cover
all possible organisms, antibiotics with a wide spectrum activity must be used in most cases. …

… From this clinical perspective, we observed very good performances for ceftazidime (in
non-AmpC producing strains), cefepime (all strains), fluoroquinolones and aminoglycosides, with …

… Emergence of resistance during therн apy with the newer beta-lactam antibiotics: role of
inducible betalactamases and implications for the future. Rev Infect Dis 1983;5: 639-48. …

… betalactamase hydrolysis, yet some beta-lactamaseproducing gram-negative bacteria still
develop resistance. In these species, it appears that the betalactamases … of broad spectrum …

Extended-spectrum β-lactamases (ESBLs), which hydrolyse extended-spectrum cephalosporins
and are inhibited by clavulanic acid, are spreading among Enterobacteriaceae. The …

… pneumoniae is intrinsically resistant to penicillins via the production of a narrow-spectrum
beta- lactamase (of SHV, LEN or OKP type), which is constitutively expressed. Two studies …

… in-hospital treatment and intravenous administration of broad-spectrum antibiotics[60-62]. …
Carbapenem Risk of extended-spectrum β-lactamase-producing gram negative bacteria …

… interesting compounds from a clinical perspective are the two … against many extended-spectrum
β-lactamase–producing … is not uncommon in extended-spectrum β-lactamase producers, …

The complexities of Shigellosis and a highly transmissible gastrointestinal illness brought on
by pathogenic Shigella spp., are examined in this book chapter. This disease is extremely …