Potency and antimicrobial spectrum update for piperacillin/tazobactam (2000): emphasis on its activity against resistant organism populations and generally untested …

DM Johnson, DJ Biedenbach, RN Jones - Diagnostic microbiology and …, 2002 - Elsevier
… inhibitors (clavulanic acid, sulbactam, tazobactam) with older penicillins (ticarcillin, ampicillin,
piperacillin), the strong synergistic effect provides a dramatically expanded spectrum of …

Pharmacokinetic and pharmacodynamic profile of high dose extended interval piperacillintazobactam

MK Kim, D Xuan, R Quintiliani… - Journal of …, 2001 - academic.oup.com
… interval for P/T can be extended if larger doses are administered. This same strategy has
been investigated for other extended spectrum penicillins with favourable results. Moreover, …

Piperacillin-Tazobactam for Pseudomonas aeruginosa Infection: Clinical Implications of an Extended-Infusion Dosing Strategy

TP Lodise Jr, B Lomaestro… - Clinical Infectious …, 2007 - academic.oup.com
… implications of extended infusion of piperacillin-tazobactam therapy for … piperacillin-tazobactam
therapy for a P. aeruginosa infection that was susceptible to piperacillin-tazobactam

Clinical significance of extended-spectrum beta-lactamases

JP Quinn - European Journal of Clinical Microbiology and …, 1994 - Springer
… especially exposure to extended-spectrum beta-lactam agents. In … the spread of
extended-spectrum beta-lactamases among … the activity of piperacillin/tazobactam and imipenem …

Susceptibilities of ESBL-producing enterobacteriaceae to ertapenem, meropenem and piperacillin-tazobactam with and without clavulanic acid

D Raveh, AM Yinnon, E Broide, B Rudensky - Chemotherapy, 2007 - karger.com
… reported by our laboratory as being sensitive to extended spectrum lactam agents [8] , but
… against ertapenem, meropenem and piperacillin-tazobactam, according to the manufacturer’…

Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp …

PNA Harris, AY Peleg, J Iredell, PR Ingram, S Miyakis… - Trials, 2015 - Springer
piperacillin-tazobactam, may be non-inferior to carbapenems for the treatment of bloodstream
infection caused by extended-spectrum beta-lactamase… resistance to expanded spectrum

In vitro killing of parenteral beta-lactams against standard and high inocula of extended-spectrum beta-lactamase and non-ESBL producing Klebsiella pneumoniae

DS Burgess, RG Hall II - Diagnostic microbiology and infectious disease, 2004 - Elsevier
… However, this clearly did not hold true for piperacillin/tazobactam in this study. Piperacillin/tazobactam
did not show the same bactericidal activity against ESBL K. pneumoniae and non-…

[HTML][HTML] The impact of the increased use of piperacillin/tazobactam on the selection of antibiotic resistance among invasive Escherichia coli and Klebsiella …

J Lee, CE Oh, EH Choi, HJ Lee - International Journal of Infectious …, 2013 - Elsevier
… This study evaluated the impact of the increased use of piperacillin/tazobactam (TZP) on
the … Risk factors for increasing multidrug resistance among extended-spectrum beta-lactamase-…

Impact of Piperacillin/Tazobactam Use to Intestinal Colonization of Extended-spectrum-lactamase Producing Escherichia coli and Klebsiella pneumoniae

HJ SHIN, YS JANG, MR SEO, HJ PAI… - Infection and …, 2007 - pesquisa.bvsalud.org
… -spectrum b-lactamases (ESBLs) pose a serious clinical … Use of piperacillin/tazobactam
instead of extended-spectrum … using piperacillin/tazobactam instead of using extended-spectrum

Differences in the changes in resistance patterns to third-and fourth-generation cephalosporins and piperacillin/tazobactam among Klebsiella pneumoniae and …

G Petrikkos, A Markogiannakis… - International journal of …, 2007 - Elsevier
… Selection of Enterobacteriaceae producing extended spectrum β-lactamases (ESBLs) is a
… reduction of broad-spectrum CEP usage and replacement by β-lactam/β-lactamase inhibitor …