… domains of DARC using chimeric receptors and monoclonal antibodies to multiple extracellular
domains … binding to structures in the amino terminal extracellular domain (E1). Scatchard …

… receptor. In a structure–function study, we analysed the binding of chemokines and anti-Fy
monoclonal antibodies (… spread out on the four extracellular domains (ECDs). Using synthetic …

… of the Duffyantigen/receptor for chemokines (DARC) is given by its extracellular NH 2 -… Fy3
epitopes, localized in the first and fourth extracellular domains of DARC, respectively, and the …

… extracellular amino-terminal domain of DARC, noted ECD1, which carries the Fy a/b and
Fy6 blood group antigens [… close association of the four extracellular domains of DARC (noted …

… amino acids of the amino-terminal extracellular domain of DARC and those encoding five
amino acid residues in the amino-terminal extracellular domain of IL-8RB ending 20 residues …

… Our results indicate that two independently obtained mAbs, BG6 and i3A, recognize the
same linear epitope in the extracellular domain of the Duffy polypeptide chain. The epitope …

… favor of a selection pressure on the extracellular domains involved in ligand specificity. The
… divergence on the amino-terminal extracellular domain. Analysis of the deduced amino acid …

… and their ligands involves initial interaction with the N-terminal extracellular domains of
the receptor, generally mediated by electrostatic forces. Modifications of these regions, using …

… third extracellular loop, and there is a disulfide bond between cysteine 51, at the amino terminal
domain, and cysteine 276, at the third extracellular … antigen receptor for chemokines. Mol …

… extracellular N-terminal domain, which bears the blood group determinants, is linked with
the fourth extracellular domain … of the extracellular domains of the Duffy antigen/receptor for …