… dendrites of some neurons in the central nervous system (CNS). It was first reported by …
The connection between this extracellular matrix (ECM) structure and maturation of the CNS …

… An important approach to repair the injured CNS is therefore to harness, promote and refine
… extracellular matrix (ECM). While the ECM typically provides a supportive framework to CNS …

… The human central nervous system (CNS) is a highly complex biological tissue, … extracellular
matrix (ECM) that makes up approximately 20% of the total volume of the adult CNS (Refs 3…

… repair is to mimic exactly the biological and mechanical properties of the cell microenvironment
seen in vivo. In native tissue, the cells reside in the extracellular matrix … CNS tissue repair …

… ) and have a potent inhibitory influence on regeneration of the CNS [1]. After injury to the CNS,
a … ChABC is often used in combination with other repair strategies to facilitate the greatest …

… Promoting CNS Plasticity and Rehabilitation The connection between the extracellular
matrix (ECM) and the control of plasticity was first made when it became clear that injection of …

… Spinal cord and brain injuries lead to complex cellular and molecular interactions within the
central nervous system in an attempt to repair the initial tissue damage. Many studies have …

… still cannot resolve all the active and dynamic CNS physiology. Indeed, recent studies have
… by the neural extracellular matrix (nECM) to the so-called, tetrapartite synapse.2, 3 CNS …

… During CNS development, the ECM provides a microenvironment that regulates cell … the
adult CNS, it contributes to maintenance of synaptic stability and regulates repair following injury…

… , and discuss how the ECM may be targeted to promote the repair of myelin. The focus of
this article is the ECM in the adult CNS. In particular, we highlight the emerging roles of …