Increased extracellular matrix remodeling is associated with tumor progression in human hepatocellular carcinomas

N Théret, O Musso, B Turlin, D Lotrian… - Hepatology, 2001 - journals.lww.com
… , secrete abundant extracellular matrix proteins, including collagen I,13 and express
MMP214-16 at high levels. We have recently shown that extracellular matrix deposition induces …

Hepatic stellate cells and extracellular matrix in hepatocellular carcinoma: more complicated than ever

V Carloni, TV Luong, K Rombouts - Liver International, 2014 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third …
and issues regarding hepatic stellate cells, extracellular matrix dynamics, liver fibrosis/cirrhosis …

Hepatocellular carcinomas, exhibiting intratumor fibrosis, express cancer-specific extracellular matrix remodeling and WNT/TGFB signatures, associated with poor …

R Desert, W Chen, X Ge, R Viel, H Han, D Athavale… - Hepatology, 2023 - journals.lww.com
… Although HCC is generally poorly fibrogenic, some tumors harbor focal intratumor
extracellular matrix (ECM) deposits called “fibrous nests.” To date, the molecular …

Evaluation of hepatocellular carcinoma aggressiveness by a panel of extracellular matrix antigens.

WF Grigioni, S Garbisa, A D'errico… - The American journal …, 1991 - ncbi.nlm.nih.gov
… Our series comprised 30 hepatocellular carcinomas in cirrhotic livers drawn from patients
surgically resected at Bologna University between 1984 and 1986. All patients had complete …

[PDF][PDF] The extracellular matrix in hepatocellular carcinoma: Mechanisms and therapeutic vulnerability

AM Roy, R Iyer, S Chakraborty - Cell Reports Medicine, 2023 - cell.com
… by a "disorganized" extracellular matrix (ECM) that sensitizes cancer cells toward mechanical
stress, signaling, and structural alterations. In hepatocellular carcinoma (HCC), lack of …

Extracellular matrix remodeling in hepatocellular carcinoma: effects of soil on seed?

XZ Wu, D Chen, GR Xie - Medical hypotheses, 2006 - Elsevier
… progression of hepatocellular carcinoma. On the one hand, extracellular matrix provides the
… proliferation, differentiation and metastasis of hepatocellular carcinoma. On the other hand, …

[HTML][HTML] Extracellular matrix collagen I promotes the tumor progression of residual hepatocellular carcinoma after heat treatment

R Zhang, M Ma, XH Lin, HH Liu, J Chen, J Chen… - BMC cancer, 2018 - Springer
extracellular matrix (ECM) in modulating the progression of residual hepatocellular carcinoma
… the local tissue microenvironment such as extracellular matrix (ECM) proteins. Besides …

Extracellular matrix transcriptome dynamics in hepatocellular carcinoma

MB Duncan - Matrix Biology, 2013 - Elsevier
… key extracellular matrix collagens, glycoproteins, and proteoglycans in hepatocellular
carcinoma… This analysis also reveals alternative expression of extracellular matrix gene transcript …

Extracellular matrix protein 1, a novel prognostic factor, is associated with metastatic potential of hepatocellular carcinoma

H Chen, WD Jia, JS Li, W Wang, GL Xu, JL Ma… - Medical Oncology, 2011 - Springer
Extracellular matrix protein 1 (ECM1) is a glycoprotein involved in a number of biologic
processes. To investigate the expression of ECM1 in hepatocellular carcinoma (HCC) and …

The extracellular matrix in hepatocellular carcinoma shows different localization patterns depending on the differentiation and the histological pattern of tumors …

T Torimura, T Ueno, S Inuzuka, M Kin, H Ohira… - Journal of …, 1994 - Elsevier
… of the extracellular matrix, and compared their localization patterns in relation to the grade
of tumor differentiation and the histological pattern of hepatocellular carcinoma. Type I, III, and …