[HTML][HTML] Extracellular matrix proteins in metastases to the liver–Composition, function and potential applications

H Nyström - Seminars in Cancer Biology, 2021 - Elsevier
Cancer research has expanded its focus now also to include the importance of … Extracellular
Matrix (ECM) and its composition, function and potential applications in the aspect of liver

The liver metastatic niche: modelling the extracellular matrix in metastasis

J Drew, LM Machesky - Disease Models & Mechanisms, 2021 - journals.biologists.com
cancer cells, and that cancer cell-extracellular matrix interactions … The extracellular matrix is
the complex and dynamic non-… focus on how extracellular matrix dynamics contribute to liver

[HTML][HTML] Tumor decellularization reveals proteomic and mechanical characteristics of the extracellular matrix of primary liver cancer

GS van Tienderen, J Conboy, I Muntz, J Willemse… - Biomaterials …, 2023 - Elsevier
… of extracellular matrix. One of the major goals of this study was to uncover the categorical
constituents of human liver cancer extracellular matrices, … of the extracellular matrix on various …

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver

A Naba, KR Clauser, CA Whittaker, SA Carr… - BMC cancer, 2014 - Springer
… Because of the very small amount of extracellular matrix in the normal liver, we were not
able to analyze reliably the liver ECM from individual patient samples (on average 50 – 75 mg). …

Extracellular matrix and its therapeutic potential for cancer treatment

J Huang, L Zhang, D Wan, L Zhou, S Zheng… - … and Targeted Therapy, 2021 - nature.com
… The extracellular matrix (ECM) is one of the major … During tumorigenesis, the interplay
between cancer cells and the … of promising therapeutic targets for cancer treatment. Herein, we …

Linking extracellular matrix agrin to the hippo pathway in liver cancer and beyond

S Chakraborty, W Hong - Cancers, 2018 - mdpi.com
… In addition to the accumulation of agrin in the liver of rats … of agrin as an extracellular matrix
sensor that stabilized focal … form an oncogenic axis in liver cancer; therefore, explaining its …

Hepatic stellate cells and extracellular matrix in hepatocellular carcinoma: more complicated than ever

V Carloni, TV Luong, K Rombouts - Liver International, 2014 - Wiley Online Library
Liver cancer progresses in a large percentage of cases during the clinical course of
chronic fibro-inflammatory liver … stellate cells, extracellular matrix dynamics, liver fibrosis/cirrhosis …

Extracellular matrix and liver disease

E Arriazu, M Ruiz de Galarreta, FJ Cubero… - Antioxidants & redox …, 2014 - liebertpub.com
… This review drives from the composition and sources of the extracellular matrix (ECM) in
healthy and injured liver to the potential mechanism driving fibrosis resolution such as …

The alterations in the extracellular matrix composition guide the repair of damaged liver tissue

M Klaas, T Kangur, J Viil, K Mäemets-Allas… - Scientific reports, 2016 - nature.com
… restoration of functional liver tissue through proliferation of … the extracellular matrix (ECM)
1 . Furthermore, such life-threatening pathological conditions as liver cirrhosis and liver cancer

Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix

AE Yuzhalin, AN Gordon-Weeks, ML Tognoli… - Nature …, 2018 - nature.com
… in cancer. Here we show that citrullination of the extracellular matrix by cancer cell derived
… of liver metastases from colorectal cancer (CRC). Using proteomics, we demonstrate that …