Neuronally derived extracellular vesicles: an emerging tool for understanding Alzheimer's disease

LS Watson, ED Hamlett, TD Stone… - Molecular …, 2019 - Springer
… genetic material to ensue disease propagation. Small extracellular vesicles are produced via
… the role of these neuronally-derived extracellular vesicles (NDEVs) in the propagation of AD…

Extracellular vesicle biology in Alzheimer's disease and related tauopathy

AM DeLeo, T Ikezu - Journal of Neuroimmune Pharmacology, 2018 - Springer
Extracellular vesicles (EVs) are physiological vesicles secreted from most eukaryotes and
contain cargos of their cell of origin. EVs, and particularly a subset of EV known as exosomes, …

Extracellular vesicles as an emerging tool for the early detection of Alzheimer's disease

TR Li, XN Wang, C Sheng, YX Li, FZT Li, Y Sun… - Mechanisms of ageing …, 2019 - Elsevier
Alzheimer’s disease (AD) is characterized by a series … extracellular vesicle that serves as
a cell-to-cell communication messenger, is an emerging liquid biopsy tool for various diseases

Biomarker potential of brain‐secreted extracellular vesicles in blood in Alzheimer's disease

AP Badhwar, AS Haqqani - Alzheimer's & Dementia: Diagnosis …, 2020 - Wiley Online Library
disease AND exosomes AND blood; (5) Alzheimer's disease AND therapy AND extracellular
vesicles, and (6) Alzheimer's diseaseAlzheimer's disease AND therapy AND extracellular

Extracellular vesicles of Alzheimer's disease patients as a biomarker for disease progression

A Aharon, P Spector, RS Ahmad, N Horrany… - Molecular …, 2020 - Springer
Alzheimer’s disease (AD) is a progressive neurodegenerative brain pathology and the most
common form of dementia. Evidence suggests that extracellular vesicles (EVs) containing …

Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues

S Muraoka, AM DeLeo, MK Sethi… - Alzheimer's & …, 2020 - Wiley Online Library
… and machine learning of extracellular vesicles (EVs) isolated from Alzheimer's disease (AD) …
Machine learning model to identify Alzheimer's disease (AD) brain-specific extracellular

Extracellular vesicles in Alzheimer's disease: friends or foes? Focus on aβ-vesicle interaction

P Joshi, L Benussi, R Furlan, R Ghidoni… - International journal of …, 2015 - mdpi.com
Alzheimer’s disease (AD). Among other transfer modes, Aβ and tau dissemination has been
suggested to occur through release of Extracellular Vesicles (… which bind to extracellular Aβ, …

Microglia-derived extracellular vesicles in Alzheimer's Disease: A double-edged sword

T Trotta, MA Panaro, A Cianciulli, G Mori… - Biochemical …, 2018 - Elsevier
Extracellular vesicles (EVs), based on their origin or size, can be classified as apoptotic
bodies, microvesicles (MVs)/microparticles (MPs), and exosomes. EVs are one of the new …

Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons

Z Ruan, D Pathak, S Venkatesan Kalavai… - Brain, 2021 - academic.oup.com
Alzheimer’s disease extracellular vesicles were significantly … to prodromal Alzheimer’s
disease or control extracellular vesicles as … Alzheimer’s disease extracellular vesicles were more …

Blood extracellular vesicles carrying synaptic function‐and brain‐related proteins as potential biomarkers for Alzheimer's disease

…, Alzheimer's Disease Neuroimaging … - Alzheimer's & …, 2023 - Wiley Online Library
… Development of novel, flow cytometry-based assays for central nervous system (CNS)
and Alzheimer's disease (AD) markers on plasma extracellular vesicles (EVs). A, Example …