… Recently, extracellular vesicles (EVs) have received increasing attention in … treatment of
OA, and describe their mechanisms. Next, we review clinical studies using EVs for OA treatment. …

… early diagnosis and treatment. Although stem cells can promote cartilage repair and treat
OA, problems such as immune rejection and tumorigenicity persist. Extracellular vesicles (EVs) …

… Suggestions for OA treatment include regulation of gene expressions via the use of …
extracellular vesicles (EVs) with the use of advanced techniques would be an efficient OA treatment. …

… Schematic representation of the roles that extracellular vesicles released by synovial joint
cells could hypothetically play during the development of osteoarthritis (OA) based on the …

… for their therapeutic potential in treating joint injury and osteoarthritis, most commonly those
… osteoarthritis [17]. For instance, intra-articular injections of MSCs to treat knee osteoarthritis …

… Although cell therapy has made significant progress in the treatment of OA and cartilage …
that extracellular vesicles (EVs) play an important role in the progression and treatment of OA. …

… in extracellular vesicles (EVs), including exosomes, are a crucial aspect of MSC-based
treatment … biological processes associated with cartilage extracellular matrix (ECM) degradation …

… To date, the treatment for OA involves pain … extracellular vesicles (EV) therapy has been
suggested as a potential therapeutic strategy for OA in an attempt to replace invasive treatments. …

… ’ study, effective treatment is rare for this chronic disease. Extracellular vesicles (EVs),
including exosomes, microvesicles, and apoptosis bodies, are nano-sized vesicles with a cargo …

… Therefore, the use of MSCs-derived extracellular vesicles in the treatment of some
degenerative diseases is an excellent treatment strategy. SMSCs have the advantages of easy …