[HTML][HTML] A role for extracellular vesicles in SARS-CoV-2 therapeutics and prevention

J Machhi, F Shahjin, S Das, M Patel… - Journal of Neuroimmune …, 2021 - Springer
… vaccine system against the severe acute respiratory syndrome coronavirus 2 (SARS CoV-2)
infection. In this review efforts to use EVs to contain SARS CoV-2 and affect the current viral …

[HTML][HTML] Promising extracellular vesicle-based vaccines against viruses, including SARS-CoV-2

B Sabanovic, F Piva, M Cecati, M Giulietti - Biology, 2021 - mdpi.com
Simple Summary Extracellular vesicles (EVs) allow cell-to-cell communication and can
induce a strong immune response, by presenting antigens. EVs can be engineered to display …

[HTML][HTML] Extracellular vesicles mediate antibody-resistant transmission of SARS-CoV-2

B Xia, X Pan, RH Luo, X Shen, S Li, Y Wang, X Zuo… - Cell discovery, 2023 - nature.com
… of resistant SARS-CoV-2 variants, little is known about how SARS-CoV-2 … of extracellular
vesicle (EV)-mediated cell-to-cell transmission of SARS-CoV-2, which facilitates SARS-CoV-2 …

[HTML][HTML] Circulating platelet-derived extracellular vesicles are a hallmark of Sars-Cov-2 infection

G Cappellano, D Raineri, R Rolla, M Giordano… - Cells, 2021 - mdpi.com
Sars-Cov-2 infection causes fever and cough that may … )-derived extracellular vesicles (EVs)
as biomarkers for Sars-Cov-… two independent cohorts of Sars-CoV-2+ (n = 69), Sars-Cov-2− (…

[HTML][HTML] Liposome-mediated detection of SARS-CoV-2 RNA-positive extracellular vesicles in plasma

B Ning, Z Huang, BM Youngquist, JW Scott… - Nature …, 2021 - nature.com
… into extracellular vesicles. Here we describe an assay approach in which extracellular vesicles
… liposomes to sensitively amplify and detect a SARS-CoV-2 gene target. This approach …

[HTML][HTML] Anti‐SARSCoV‐2 effect of extracellular vesicles released from mesenchymal stem cells

S Chutipongtanate, S Kongsomros… - … Extracellular Vesicles, 2022 - ncbi.nlm.nih.gov
… ‐SARSCoV‐2 effect of MSC‐EVs. In this study, MSC‐EV was referred to as the exosome
(or small EV) subpopulation of extracellular vesicles. … (to separate extracellular vesicles from …

Extracellular vesicles containing ACE2 efficiently prevent infection by SARSCoV‐2 Spike protein‐containing virus

F Cocozza, N Névo, E Piovesana… - … extracellular vesicles, 2020 - Wiley Online Library
SARS-CoV-2 entry is mediated by binding of the spike protein (S) to the … extracellular vesicles
(EVs) exposing ACE2 and demonstrate that ACE2-EVs are efficient decoys for SARS-CoV-…

Intrinsic factors behind long‐COVID: II. SARSCoV‐2, extracellular vesicles, and neurological disorders

YA El‐Maradny, A Rubio‐Casillas… - Journal of Cellular …, 2023 - Wiley Online Library
… response that, rather than defending against the virus, starts to target the healthy cells of …
of extracellular vesicles (ECVs) on the neurological system in long-COVID. In fact, SARS-CoV-2 …

[HTML][HTML] Circulating extracellular vesicles are endowed with enhanced procoagulant activity in SARS-CoV-2 infection

C Balbi, J Burrello, S Bolis, E Lazzarini, V Biemmi… - …, 2021 - thelancet.com
… who tested positive for SARS-CoV-2 on nasopharyngeal swab … and confirmed diagnosis of
SARS-CoV-2 infection were … expressed EV surface marker in SARS-CoV-2 positive patients …

[HTML][HTML] Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2

L El-Shennawy, AD Hoffmann, NK Dashzeveg… - Nature …, 2022 - nature.com
… Herein, we report an increase in circulating extracellular vesicles (EVs) that express ACE2
(… neutralizes SARS-CoV-2 infection by competing with cellular ACE2. Compared to vesicle-…