[HTML][HTML] Potential roles of extracellular vesicles as biomarkers and a novel treatment approach in multiple sclerosis

M Gutiérrez-Fernández, F de la Cuesta… - International Journal of …, 2021 - mdpi.com
… However, despite the importance of the role of oligodendrocytes in MS, to our knowledge
there are no studies that have isolated these vesicles from the blood of MS patients. …

Sulfatides in extracellular vesicles isolated from plasma of multiple sclerosis patients

AL Moyano, G Li, AI Boullerne… - Journal of …, 2016 - Wiley Online Library
sclerosis (MS). They are mobilized in biological fluids, but little is known about the participation
of extracellular vesicles (… spectrometry in EVs isolated from patients with MS and healthy …

[HTML][HTML] Pathological proteins are transported by extracellular vesicles of sporadic amyotrophic lateral sclerosis patients

D Sproviero, S La Salvia, M Giannini… - Frontiers in …, 2018 - frontiersin.org
… in the body fluids by extracellular vesicles (EVs). EVs are spherical vesicles, which are …
In this study we characterized MVs and EXOs isolated from plasma of sporadic ALS patients

[HTML][HTML] Therapeutic potential of extracellular vesicles derived from human mesenchymal stem cells in a model of progressive multiple sclerosis

F Laso-García, J Ramos-Cejudo, FJ Carrillo-Salinas… - PloS one, 2018 - journals.plos.org
… The majority of available treatments for patients with MS are … in most patients and in
progressive forms of the disease [9]. … vivo CNS myelination via extracellular vesicle (EV) signalling …

[HTML][HTML] Extracellular vesicles in multiple sclerosis: what are they telling us?

M Sáenz-Cuesta, I Osorio-Querejeta… - Frontiers in cellular …, 2014 - frontiersin.org
Extracellular vesicles have been also classified as a function of their cell origin … patients
had the highest counts for the three subtypes of EVs while secondary progressive patients were …

[HTML][HTML] Emerging role of extracellular vesicles in the pathophysiology of multiple sclerosis

E Dolcetti, A Bruno, L Guadalupi, FR Rizzo… - International journal of …, 2020 - mdpi.com
… progressive multiple sclerosis (SPMS). About 15% of MS patients directly develops a … are
classified as primary progressive multiple sclerosis (PPMS) patients [25]. Clinical classification …

Identification of a circulating miRNA signature in extracellular vesicles collected from amyotrophic lateral sclerosis patients

D Saucier, G Wajnberg, J Roy, AP Beauregard… - Brain Research, 2019 - Elsevier
… are released in extracellular vesicles (EVs) in PALS remains incomplete. The current study
was initiated to detect the presence of miRNAs in extracellular vesicles isolated from PALS, …

[HTML][HTML] The first dose of fingolimod affects circulating extracellular vesicles in multiple sclerosis patients

M Sáenz-Cuesta, A Alberro, M Muñoz-Culla… - International Journal of …, 2018 - mdpi.com
Extracellular vesicles (EVs) are membrane-bound particles … blood of multiple sclerosis (MS)
patients and postulated them as … EVs from fingolimod-treated MS patients in order to assess …

[HTML][HTML] CNS endothelial derived extracellular vesicles are biomarkers of active disease in multiple sclerosis

M Mazzucco, W Mannheim, SV Shetty… - Fluids and Barriers of the …, 2022 - Springer
… We believe extracellular vesicles (EV) isolated from plasma are … derived EV will be increased
in MS patients with active disease. … (HC), RRMS patients with active disease not receiving …

Counting of peripheral extracellular vesicles in Multiple Sclerosis patients by an improved nanoplasmonic assay and dynamic light scattering

A Mallardi, N Nuzziello, M Liguori, C Avolio… - Colloids and Surfaces B …, 2018 - Elsevier
Extracellular vesicles (EVs) are vesicles naturally secreted by the … of vesicles. The proposed
analytical protocol is successfully applied to a small cohort of Multiple Sclerosis patients