… donor chimerism (DC) is predictive for relapse. In addition, we comprehensively determined
the impact of several other disease- … Extramedullary manifestations were observed in 33% of …

… disease progression question the more widespread use of allo SCT. The induction of an early
complete donor chimerism (… Interestingly, data on chimerism analysis are relatively scarce …

… The kinetics of increasing donor chimerism at this early stage post-transplant is apparently
produced by committed progenitor cells,24 and the correlation with sustained engraftment …

… All three cases, in which results were available, had complete donor chimerism at the
time chloroma was diagnosed. Acute or chronic GvHD were present in two patients each. …

… In support of this study, Pearce et al (24) also reported donor chimerism in four of eight cases
in … It should be emphasized that the latter two studies investigated the contribution of donor-…

… Longitudinal monitoring of donor chimerism after HCT … of patients who experienced relapse
or disease progression. A high … -third had extramedullary progression of the disease [102]. A …

… The positive predictive value of declining donor chimerism for isolated extramedullary relapse
was also the lower one (10%) in our study. Ohashi H et al. [27] also suggest that the graft-…

… Here, we describe a clinical case with unusual extramedullary presentation of an allograft-…
donor-derived. To our knowledge, this is the first report demonstrating allograft-localized donor…

… Shorter PFS was associated with relapse before autologous HCT and <95% donor chimerism
at 3 months after allogeneic HCT. The response to therapy and the OS/PFS were similar in …

… with extramedullary disease (EMD) and high-risk cytogenetics is not yet defined. Here, we
analyzed clinical and cytogenetic data from 488 adult myeloma patients with EMD undergoing …