… While the identity of the second mutant CFTR allele in these primary nasal epithelial cells
is unknown, we do know that it is not W1282X, F508, N1303K, G542X, G551D, or R553X. …

… normal human airway epithelial cells also fail to detect CFTR, due to its low amounts. …
epithelial cells. Because we were unable to measure the low amount of CFTR protein in these cells…

… of ∆F508-CFTR may represent a … CFTR endocytosis, we propose that interfering with the
c-Cbl mediated endocytic recruitment of ∆F508-CFTR may increase stability of ∆508-CFTR in …

… CFTR in Human Airway Epithelial Cells In order to follow the trafficking of rescued ΔF508
CFTR at the cell … -4a on ΔF508 CFTR biogenesis in human airway epithelial cells (CFBE41o-ΔF…

… expression, and chloride transport properties in gallbladder epithelial cells from nine F508
homozygous … Our results suggest that epithelial structural alterations aggravate F508 CFTR …

… then tested in the FRT epithelial cell line expressing ΔF508-CFTR using Ussing chamber …
delta F508-homozygous cystic fibrosis patients: partial restoration of nasal epithelial CFTR …

… The mutated CFTR anion channel is not fully … epithelial cells of patients with cystic fibrosis.
Low temperature or inhibition of histone deacetylases can partly rescue ∆F508 CFTR cellular …

… This analysis revealed that epithelial cells account for approximately 87% of all cells in the
non–CF, carrier, and CF samples, with no significant differences among the three groups (Fig. …

… cystic fibrosis transmembrane conductance regulator (CFTR) mutation causing cystic fibrosis,
… primary cultures of human bronchial epithelial cells from a homozygous ∆F508 CF patient. (…

… of human bronchial epithelial cells derived either from F508del CFTR homozygous donors,
CF-… delta F508 cystic fibrosis transmembrane conductance regulator in airway epithelial cells. …