… Hemophilia A is an X-linked recessive disorder caused by a deficiency in factor VIII (FVIII).
The … Molecular analysis of factor VIII and factor IX gene in hemophilia patients: identification of …

… factor VIII inhibitors among patients treated with plasma-derived factor VIII containing von
Willebrand factor … included 131 patients (66 patients treated with plasma-derived factor VIII and …

… We evaluated 574 consecutive patients with severe hemophilia A (factor VIII activity, <0.01
IU per milliliter) who were born between 2000 and 2010 and collected data on all clotting-…

… patients with non-severe hemophilia A, we lack detailed knowledge on the timing of treatment
with factor VIII (… patients with severe hemophilia A treated with non-replacement therapies. …

… chains of factor VIII, as do inhibitors in patients with hemophilia treated only with plasma-derived
factor VIII 12,13,18,19 . These data do not suggest that recombinant factor VIII has a …

… in patients with hemophilia A is the development of alloantibodies that inhibit factor VIII … ,
replacement of the missing clotting factor by infusion of factor VIII becomes less effective. Once …

… patients with severe hemophilia, born between 1944 and 1995. To improve efficiency we
measured factor VIII half-life in 42 patients … of phenotypes of severe hemophilia. We assessed …

… price and the risk of occurrence of factor VIII inhibitory alloantibodies. With this as … patients
with severe hemophilia A: previously untreated patients, multiply treated patients, and patients …

… However, their hemostatic efficacy does not reach the overall level of success obtained with
FVIII replacement in hemophilia patients without inhibitors, and no validated strategies are …

… of factor VIII replacement therapy in patients with hemophilia A. To … VIII antibody formation in
a murine model of hemophilia A. … factor VIII inhibitor antibodies in patients with hemophilia A. …