… Atrial fibrillation (AF) is the most common clinical tachyarrhythmia. In Europe, AF is expected
… investigated in depth since the first report of familial atrial fibrillation (FAF) in 1936. Despite …

… responsible for a familial form of the disease. Familial atrial fibrillation is probably very
uncommon, 5 but we located a small family in Spain in which atrial fibrillation segregates as an …

… %) and premature familial AF occurred among 351 participants (7.9%). Atrial fibrillation
occurred more frequently among participants with familial AF than without familial AF (unadjusted …

… The aims of this study were to identify and characterize familial cases of atrial fibrillation (AF)
in our clinical practice and to determine whether AF is genetically heterogeneous. …

… Atrial fibrillation (AF) remains one of the most common and challenging arrhythmias encountered
in clinical practice. While familial … the arrhythmia. Despite the limited prevalence of the …

… To elucidate the mechanism by which a mutation in NPPA could lead to familial atrial
fibrillation, we first showed that the mutation we identified results in the production of a mutant …

Atrial fibrillation (AF), the most common arrhythmia, is a growing epidemic with substantial
morbidity and economic burden. Mechanisms underlying vulnerability to AF remain poorly …

Aims This research was aimed at screening connexin40, a cardiac gap junction protein alpha
5, for genetic defects in patients with familial atrial fibrillation (AF). Methods The subjects …

… Atrial fibrillation can occur on a familial basis, pointing to a genetic cause of the arrhythmia
in some individuals. Hereditary AF in three families was recently linked to a locus between …

Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice.
We first reported an S140G mutation of KCNQ1, an α subunit of potassium channels, in one …