… We investigate in the paper the use of various FH scores to capture this ‘family risk’ factor.
In such studies, the persons interviewed are asked to give information regarding their relatives…

… family history reports into an overall score. We compare the predictive validity of different
family history scores… We computed four family history scores for each disorder: (1) a simple …

… risk factors and included a term for the interaction between family history and GRS50. Self-reported
family history was associated with incident CHD events after adjustment for …

… to accurately identify family history, and found that a positive family history (defined as ⩾1 …
a positive family history carried higher GRS burden compared with those without family history. …

… from family history (FH) of psychiatric illnesses. The methods range from a simple dichotomous
or count scores to those quantifying as weighted risks such as the Family history density (…

… between PRS and family history, as well as whether PRS were still significant after
accounting for family history, we also fit models which included PRS, family history, and their …

… A scoring system that reflects a clinically significant familial risk of colorectal neoplasia
may … In this study, a scoring system for colorectal cancer risk according to family history is …

… The data address the question of family history and current pathological gambling. The
questions for grandparents were phrased as "to your knowledge did either or both of your …

… of schizophrenia/psychoses was mediated through the polygenic risk score. … risk score,
family psychiatric history, and socioeconomic status. Our study demonstrated that family history of …

… Polygenic risk scores (PRSs) derived from genotype data and family history (FH) of disease
… In conclusion, including family history improves the accuracy of polygenic risk scores, …