Beneficial effects of mangiferin on hyperlipidemia in high‐fat‐fed hamsters

F Guo, C Huang, X Liao, Y Wang, Y He… - Molecular nutrition & …, 2011 - Wiley Online Library
… and its possible mechanism, we first systematically studied the effect of mangiferin on lipid
mangiferin has a specific effect on TG and FFA metabolism in hamsters fed a high-fat diet. …

[HTML][HTML] Mangiferin decreases plasma free fatty acids through promoting its catabolism in liver by activation of AMPK

Y Niu, S Li, L Na, R Feng, L Liu, Y Li, C Sun - PloS one, 2012 - journals.plos.org
mangiferin has effects on FFA metabolism in hyperlipidemic rats. Wistar rats were fed a
high-fat diet and administered mangiferin … systematically the effect of mangiferin on FFA levels …

Evaluation of Antiobesity Effect of Mangiferin in Adipogenesis‐Induced Human Mesenchymal Stem Cells by Assessing Adipogenic Genes

P Subash‐Babu, AA Alshatwi - Journal of Food Biochemistry, 2015 - Wiley Online Library
… The Effects of Mangiferin on Gene Expression Fat accumulation and adipogenic gene
expression were decreased by mangiferin treatment in differentiation-induced hMSCs. PPARγ, …

Mangiferin ameliorates fatty liver via modulation of autophagy and inflammation in high-fat-diet induced mice

H Wang, YY Zhu, L Wang, T Teng, M Zhou… - Biomedicine & …, 2017 - Elsevier
… Therefore, in the present study, we evaluated the effects of three different concentrations of
mangiferin on NAFLD in HFD-fed mice. We investigated whether mangiferin could affect the …

Mangiferin suppresses endoplasmic reticulum stress in perivascular adipose tissue and prevents insulin resistance in the endothelium

X Xu, Y Chen, J Song, F Hou, X Ma, B Liu… - European journal of …, 2018 - Springer
… examination of adipocytes, and endothelial tissue in high-fat diet-fed mice also showed that
oral administration of Mangiferin inhibited ER stress and NLRP3 induction in PVAT, and then …

[HTML][HTML] Mangiferin improves hepatic lipid metabolism mainly through its metabolite-norathyriol by modulating SIRT-1/AMPK/SREBP-1c signaling

J Li, M Liu, H Yu, W Wang, L Han, Q Chen… - Frontiers in …, 2018 - frontiersin.org
… , and increased fatty acid … effects were inhibited by Compound C in KK-A y mice liver (B1,B2).
(C) MGF-mediated lipolysis suppression effect and fatty acid oxidation activation effect

Mangiferin protects against alcoholic liver injury via suppression of inflammation-induced adipose hyperlipolysis

M Dong, L Li, G Li, J Song, B Liu, X Liu, M Wang - Food & function, 2020 - pubs.rsc.org
… of free fatty acid release and the amelioration of ethanol-induced liver injury. Our findings
identify that mangiferin … adipose hyperlipolysis, suggesting that mangiferin might be a potential …

Mangiferin modulation of metabolism and metabolic syndrome

EV Fomenko, Y Chi - BioFactors, 2016 - Wiley Online Library
… that MGF did not have any effect on ciglitazone-induced PPARγ activation 58. The plant
extracts, which are rich in MGF, inhibit intracellular TG and fat accumulation and reduce PPARγ2 …

Mangiferin treatment inhibits hepatic expression of acyl-coenzyme A: diacylglycerol acyltransferase-2 in fructose-fed spontaneously hypertensive rats: a link to …

X Xing, D Li, D Chen, L Zhou, R Chonan… - Toxicology and applied …, 2014 - Elsevier
… Collectively, our results suggest that mangiferin treatment ameliorates fatty liver in … effect
of mangiferin may occur independently of the hepatic signals associated with de novo fatty

Mangiferin stimulates carbohydrate oxidation and protects against metabolic disorders induced by high-fat diets

P Apontes, Z Liu, K Su, O Benard, DY Youn, X Li… - Diabetes, 2014 - Am Diabetes Assoc
… Here we report that mangiferin (MGF), a natural … effects, we determined that mice exposed
to an HFD combined with MGF exhibited a substantial shift in respiratory quotient from fatty