Insights into binding of fatty acids by fatty acid binding proteins

T Hanhoff, C Lücke, F Spener - Cellular Lipid Binding Proteins, 2002 - Springer
… Subfamily proteins bind retinoids, subfamily 11 proteins bind bulky ligands, examples are …
bile acid binding protein (I-BABP) and liver fatty acid binding protein (L-FABP) which binds 2 …

The fatty acid transport function of fatty acid-binding proteins

J Storch, AEA Thumser - Biochimica et Biophysica Acta (BBA)-Molecular …, 2000 - Elsevier
fatty acid-binding proteins (FABPs) comprise a family of 14–15 kDa proteins which bind
long-chain fatty acids. A … Mammalian fatty acid-binding proteins (FABPs) were discovered in the …

Fatty acid-binding proteins–insights from genetic manipulations

NH Haunerland, F Spener - Progress in lipid research, 2004 - Elsevier
Fatty acid-binding proteins belong to the conserved multigene family of the intracellular
lipid-binding proteins having molecular masses around 15 kDa. Members of this family have …

[HTML][HTML] Structural and functional analysis of fatty acid-binding proteins

J Storch, L McDermott - Journal of lipid research, 2009 - ASBMB
… Mapping of the hormone-sensitive lipase binding site on the adipocyte fatty acid binding
protein: … Fatty acid binding proteins from different tissues show distinct patterns of fatty acid

The emerging functions and mechanisms of mammalian fatty acidbinding proteins

J Storch, B Corsico - Annu. Rev. Nutr., 2008 - annualreviews.org
… solution structures for liver-type fatty acidbinding protein (LFABP), demonstrating specific
conformational changes between unliganded and oleate-bound proteins. (a) Superposition of …

Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets

M Furuhashi, GS Hotamisligil - Nature reviews Drug discovery, 2008 - nature.com
… Here, we discuss the central role of lipid chaperones — the fatty acid-binding proteins (FABPs)
— in lipid-mediated biological processes and systemic metabolic homeostasis through …

Unravelling the significance of cellular fatty acid-binding proteins

JFC Glatz, J Storch - Current Opinion in Lipidology, 2001 - journals.lww.com
… Requirement for the heart-type fatty acid binding protein in cardiac fatty acid utilization.
FASEB J 1999; 13:805-812. This paper provides a description of the heart-type FABP c -null …

Fatty acid binding proteins from different tissues show distinct patterns of fatty acid interactions

GV Richieri, RT Ogata, AW Zimmerman… - Biochemistry, 2000 - ACS Publications
fatty acid binding protein (ADIFAB) method, of the binding of fatty acids (FA) to human fatty
acid binding proteins (… We also measured binding of FA to a retinoic acid (CRABP-I) and a …

New insights into the structure and function of fatty acid-binding proteins

AW Zimmerman, JH Veerkamp - Cellular and Molecular Life Sciences …, 2002 - Springer
Fatty acid-binding proteins (FABPs) are members of a superfamily of lipid-binding proteins,
and … roles in fatty acid (FA) metabolism and other cellular processes. Special attention is …

Fatty acid binding protein isoforms: structure and function

F Schroeder, CA Jolly, TH Cho, A Frolov - Chemistry and Physics of Lipids, 1998 - Elsevier
… of cytosolic fatty acid binding proteins (FABPs) in mammalian tissues are now well understood,
significant advances regarding the physiological function(s) of these proteins have been …