Fatty acid metabolism and cancer development
Y Chen, P Li - Science Bulletin, 2016 - Elsevier
… pathways are altered in cancer cells. Here, we provide a brief review for the role of fatty
acid metabolism in cancer development with a special focus on fatty acid uptake and de novo …
acid metabolism in cancer development with a special focus on fatty acid uptake and de novo …
[HTML][HTML] Fatty acid activation in carcinogenesis and cancer development: Essential roles of long-chain acyl-CoA synthetases
Y Tang, J Zhou, SC Hooi, YM Jiang… - Oncology …, 2018 - spandidos-publications.com
… of fatty acid metabolism in cancer initiation and development is … Fatty acids have different
turnovers in the body: Either … a common initial step known as fatty acid activation. Long‑chain …
turnovers in the body: Either … a common initial step known as fatty acid activation. Long‑chain …
Role of fatty acid binding proteins (FABPs) in cancer development and progression
IH McKillop, CA Girardi, KJ Thompson - Cellular signalling, 2019 - Elsevier
… Uptake of free fatty acids occurs by passive diffusion across membranes and via receptors
… free fatty acid receptors and fatty acid transport proteins. As lipid chaperones, fatty acid …
… free fatty acid receptors and fatty acid transport proteins. As lipid chaperones, fatty acid …
[HTML][HTML] Role of microbiota-derived short-chain fatty acids in cancer development and prevention
R Mirzaei, A Afaghi, S Babakhani, MR Sohrabi… - Biomedicine & …, 2021 - Elsevier
… and cancer progression [21]. However, determining the function of bacterial cells in cancer
development is difficult owing to the impact of host determinants in cancer susceptibility, the …
development is difficult owing to the impact of host determinants in cancer susceptibility, the …
[HTML][HTML] Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology
FP Kuhajda - Nutrition, 2000 - Elsevier
… synthesis pathway was thought to be of little importance, as dietary lipids would provide
the necessary fatty acid for growth, development, and survival.19 This notion is essentially …
the necessary fatty acid for growth, development, and survival.19 This notion is essentially …
Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer
JV Swinnen, T Roskams, S Joniau… - … journal of cancer, 2002 - Wiley Online Library
… it corresponds to fatty acid synthase (FAS), a key metabolic enzyme that plays a central role
in the de novo biosynthesis of fatty acids.2 The preferential expression of FAS in cancer cells …
in the de novo biosynthesis of fatty acids.2 The preferential expression of FAS in cancer cells …
Fatty acid synthase and cancer: new application of an old pathway
FP Kuhajda - Cancer research, 2006 - AACR
… a significant reduction in tumor development and inhibition of mammary tumor fatty acid
synthesis (41). These data suggest that FAS inhibition may hold promise as a strategy for …
synthesis (41). These data suggest that FAS inhibition may hold promise as a strategy for …
Diverse roles of fatty acid binding proteins (FABPs) in development and pathogenesis of cancers
… FABPs, a group of lipid binding proteins modulate fatty acid metabolism, cell growth and
proliferation and cancer development. They may be used as tumor marker in some cancers. …
proliferation and cancer development. They may be used as tumor marker in some cancers. …
Short-chain fatty acids administration is protective in colitis-associated colorectal cancer development
Y Tian, Q Xu, L Sun, Y Ye, G Ji - The Journal of Nutritional Biochemistry, 2018 - Elsevier
… Reduced short-chain fatty acids (SCFAs) have been reported in patients with … cancer remains
unknown. The chemopreventive effect of SCFAs in colitis-associated colorectal cancer was …
unknown. The chemopreventive effect of SCFAs in colitis-associated colorectal cancer was …
[HTML][HTML] Role of dietary fatty acids in mammary gland development and breast cancer
M MacLennan, DWL Ma - Breast Cancer Research, 2010 - Springer
… the consumption of specific fatty acids and cancer risk. The purpose … fatty acids and cancer
risk at different life stages of the lifecycle and the contribution of specific families of fatty acids …
risk at different life stages of the lifecycle and the contribution of specific families of fatty acids …
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