Endogenous Generation and Signaling Actions of Omega‐3 Fatty Acid Electrophilic Derivatives

C Cipollina - BioMed research international, 2015 - Wiley Online Library
… Nonenzymatic generation of … esterified fatty acids. Due to their high unsaturation degree,
long chain omega-3 PUFAs are highly prone to free-radical-mediated autoxidation generating a …

Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion

V Rudolph, TK Rudolph, FJ Schopfer… - Cardiovascular …, 2010 - academic.oup.com
… This study reveals the de novo generation of fatty acid nitration products in vivo and reveals
the anti-inflammatory and potential therapeutic actions of OA-NO 2 in myocardial I/R injury. …

Endogenous formation of trans fatty acids: Health implications and potential dietary intervention

WL Hung, LS Hwang, F Shahidi, MH Pan… - Journal of Functional …, 2016 - Elsevier
… Unsaturated fatty acids naturally occur as cis configuration and most dietary trans fatty acids
… , but in vivo, they can also be formed endogenously via oxidative stress and by free radicals. …

[HTML][HTML] Arachidonic acid and other unsaturated fatty acids and some of their metabolites function as endogenous antimicrobial molecules: A review

UN Das - Journal of advanced research, 2018 - Elsevier
… Our body is endowed with several endogenous anti-microbial compounds such as interferon…
actions of various polyunsaturated fatty acids (PUFAs, mainly free acids) and their putative …

[PDF][PDF] Unsaturated fatty acids as endogenous bioregulators

GS Kogteva, VV Bezuglov - Biochemistry (Moscow), 1998 - researchgate.net
… Later studies showed that dietary fatty acids inhibit the expression of fatty acid synthase and
S14 protein in liver by suppressing the synthesis of mRNA species encoding these proteins […

[HTML][HTML] Hot topic: Endogenous production of n-3 and n-6 fatty acids in mammalian cells

KC Morimoto, AL Van Eenennaam, EJ DePeters… - Journal of dairy …, 2005 - Elsevier
… These results suggest that the cultures that were expressing FAT-1 and FAT-2 were
successfully synthesizing essential fatty acids endogenously, utilizing a fatty acid desaturation …

The role of plasma fatty acid composition in endogenous glucose production in patients with type 2 diabetes mellitus

JN Clore, J Allred, D White, J Li… - Metabolism-Clinical …, 2002 - metabolismjournal.com
… However, total saturated fatty acid (SFA) concentrations (350 … .71, P < .01), but not
monounsaturated fatty acids or PUFA. … EGP and either total FFA or fatty acid composition after a …

Peroxisome proliferator-activated receptors: a critical review on endogenous pathways for ligand generation

D Bishop-Bailey, J Wray - Prostaglandins & other lipid mediators, 2003 - Elsevier
… Activators of PPARα (see Table 1) include a variety of endogenously present fatty acids, LTB
4 and hydroxyeicosatetraenoic acids (HETEs), produced endogenously, and clinically used …

Endogenous synthesis of n− 3 PUFA modifies fatty acid composition of kidney phospholipids and eicosanoid levels in the fat-1 mouse

D Kelton, C Lysecki, H Aukema, B Anderson… - … Essential Fatty Acids, 2013 - Elsevier
… determine whether endogenous synthesis of n−3 polyunsaturated fatty acids (PUFA) in the
fat-… Wild-type and heterozygous fat-1 mice, capable of synthesizing n−3 PUFA endogenously, …

[HTML][HTML] Endogenous generation of nitro-fatty acid hybrids having dual nitrate ester (RONO2) and nitroalkene (RNO2) substituents

M Fazzari, SR Woodcock, P Rowart, K Ricart… - Redox Biology, 2021 - Elsevier
fatty acid nitration reactions that proceed by generation of … species, and an electrophilic fatty
acid nitroalkene product (NO 2 -… new insight into unsaturated fatty acid nitration mechanisms, …