The Multifunctional Family of Mammalian Fatty Acid–Binding Proteins

J Storch, B Corsico - Annual review of nutrition, 2023 - annualreviews.org
… The first fatty acid–binding protein (FABP) was detected … a family of 14–15 kDa carriers of
small hydrophobic molecules abundantly expressed in tissues that are highly active in fatty acid

Acyl carrier protein: structure–function relationships in a conserved multifunctional protein family

DM Byers, H Gong - Biochemistry and Cell Biology, 2007 - cdnsciencepub.com
fatty acid synthesis. In yeast and mammals, ACP exists as a separate domain within a large
multifunctional fatty acid … ACP are related to its multiple carrier roles in fatty acid metabolism. …

The various roles of fatty acids

CCCR De Carvalho, MJ Caramujo - Molecules, 2018 - mdpi.com
… In animals and fungi, all steps of FA biosynthesis involve one multifunctional protein complex,
the type-I fatty acid synthase (FAS), which in divided into the fungal type-Ia FAS and the …

Evolutionary origins of the multienzyme architecture of giant fungal fatty acid synthase

HST Bukhari, RP Jakob, T Maier - Structure, 2014 - cell.com
… two bacterial protein families of noncanonical fatty acid biosynthesis … The architectures of
both protein families are revealed by … by giant multifunctional enzymes, the fatty acid synthases (…

The animal fatty acid synthase: one gene, one polypeptide, seven enzymes

S Smith - The FASEB journal, 1994 - Wiley Online Library
fatty acid synthase “modules” that perform variable /3-carbon processing at successive
elongation steps, generate a structurally diverse family of … swinging arm of the multifunctional

Molecular analysis of a bifunctional fatty acid conjugase/desaturase from tung. Implications for the evolution of plant fatty acid diversity

JM Dyer, DC Chapital, JCW Kuan, RT Mullen… - Plant …, 2002 - academic.oup.com
… overall amino acid identity to the Δ 12 oleate desaturase (FAD2) family of enzymes. It is now
apparent that FAD2 has played an important role in the diversification of fatty acid structures, …

[PDF][PDF] Structural and multifunctional properties of cardiac fatty acid-binding protein: from fatty acid binding to cell growth inhibition

F Spener, T Börchers - Biochemical Society Transactions, 1992 - researchgate.net
… The cardiac fatty acid-binding protein is one type of a family … two members from this
protein family were published, that of … environment for the fatty acid bound in the fatty acid-binding …

Jasmonates meet fatty acids: functional analysis of a new acyl-coenzyme A synthetase family from Arabidopsis thaliana

L Kienow, K Schneider, M Bartsch… - Journal of …, 2008 - academic.oup.com
… It has long been assumed that these steps are catalysed by the three core enzymes of
peroxisomal fatty acid β-oxidation, acyl-CoA oxidase (ACX), multifunctional protein (MFP), and 3-…

Structure and function of eukaryotic fatty acid synthases

T Maier, M Leibundgut, D Boehringer… - Quarterly reviews of …, 2010 - cambridge.org
… enzymes, whereas in eukaryotes the fatty acid synthases (FASs) have evolved into large
multifunctional enzymes that integrate the whole process of fatty acid synthesis. During the last …

Alkamides: a critical reconsideration of a multifunctional class of unsaturated fatty acid amides

H Greger - Phytochemistry reviews, 2016 - Springer
… unsaturated, aliphatic acids with various … families consisting of various combinations of 200
acids with 23 amines. Apart from a few saturated derivatives alkamides with unsaturated acid