The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development

SBV Ramos, DJ Stumpo, EA Kennington, RS Phillips… - 2004 - journals.biologists.com
… (Zinc Finger Protein 36 Like 2, also known as TIS11D, ERF2 and BRF2) belongs to an
unusual family of zinc finger proteins containing tandem zinc-… Through their zinc fingers, these …

Role of zinc in female reproduction

TB Garner, JM Hester, A Carothers… - Biology of …, 2021 - academic.oup.com
… of conserved processes that regulate female germ cell growth, fertility, and pregnancy. …
zinc is present in one of two pools: (1) zinc that is tightly bound to proteins, such as zinc finger

Revisiting ZAR proteins: the understudied regulator of female fertility and beyond

YK Wu, HY Fan - Cellular and Molecular Life Sciences, 2022 - Springer
Zinc finger domains have been widely identified in many RBPs, which function via a Zn 2+
-dependent mechanism. Zinc finger domains may bind to nucleic acids or proteins owing to …

Sp4, a member of the Sp1-family of zinc finger transcription factors, is required for normal murine growth, viability, and male fertility

DM Supp, DP Witte, WW Branford, EP Smith… - Developmental …, 1996 - Elsevier
… While fertility of the female mutants appears normal, homozygous mutant males do not breed,
despite having histologically intact testes containing mature sperm. sp4/sp4 mutant males …

Expression of zinc finger protein 105 in the testis and its role in male fertility

H Zhou, LH Liu, H Zhang, Z Lei… - Molecular Reproduction …, 2010 - Wiley Online Library
… Five to six Zfp105þ/þ, Zfp105LacZ/þ, and Zfp105LacZ/LacZ littermates were bred with
proven fertile C57BL/6 females or males (one male/one female per cage) for 6–8 months. Litter …

Abnormal spermatogenesis and male infertility in testicular zinc finger protein Zfp318‐knockout mice

M Ishizuka, E Ohtsuka, A Inoue… - Development …, 2016 - Wiley Online Library
… Zfp318, a mouse gene with a Cys2/His2 zinc finger motif, is mainly expressed in germ cells
… , whereas Zfp318-null female mice displayed normal fertility. ZFP318 was expressed during …

Expression and distribution of the zinc finger protein, SNAI3, in mouse ovaries and pre-implantation embryos

S Guo, X Yan, F Shi, K Ma, ZJ Chen… - Journal of Reproduction …, 2018 - jstage.jst.go.jp
… silico analysis, contains the same SNAG and zinc finger domains as the mouse protein [22], …
However, Snai3 knockout mice are viable and fertile [23]. Thus, the roles of SNAI3 in female

Characterization of ΔN-Zfp36l2 mutant associated with arrest of early embryonic development and female infertility

SBV Ramos - Journal of Biological Chemistry, 2012 - ASBMB
female gamete. Zfp36l2 is a member of the tristetraprolin (TTP) family of CCCH tandem zinc
finger … The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early …

[HTML][HTML] Zinc finger RNA binding protein 2 (ZFR2) is not required for male fertility in the mouse

LM Cauchi, BJ Houston, L Nagirnaja, AE O'Connor… - Developmental …, 2022 - Elsevier
… We note Zfr2 knockout females were also fertile. … Here, we explore the function of an
uncharacterised gene, zinc finger RNA-binding protein 2 (Zfr2), a candidate male infertility gene …

The ovo gene of Drosophila encodes a zinc finger protein required for female germ line development.

M Mével‐Ninio, R Terracol, FC Kafatos - The EMBO journal, 1991 - embopress.org
… Irradiation of ovoDlI+ first instar larvae can restore female fertility, by giving rise to
homozygous wild-type germinal clones through mitotic recombination. Owing to this property, the …