[HTML][HTML] Safety and immunogenicity of a ChAdOx1 vaccine against Rift Valley fever in UK adults: an open-label, non-randomised, first-in-human phase 1 clinical trial

D Jenkin, D Wright, PM Folegatti, A Platt… - The Lancet Infectious …, 2023 - thelancet.com
Background Rift Valley fever is a viral epidemic illness prevalent in Africa that can be fatal or
result in debilitating sequelae in humans. No vaccines are available for human use. We …

[HTML][HTML] … -administration of Yellow fever vaccine with Tick-borne encephalitis or Japanese encephalitis vaccines: Results from an open label, non-randomized clinical …

JT Sandberg, M Löfling, R Varnaitė… - PLOS Neglected …, 2023 - journals.plos.org
… Here, we report the results of an open label, non-… vaccination with different commonly used
flavivirus vaccines. Healthy study participants were enrolled into cohorts receiving vaccines

[HTML][HTML] An open-label randomized clinical trial of prophylactic paracetamol coadministered with 7-valent pneumococcal conjugate vaccine and hexavalent diphtheria …

MA Rose, C Juergens, B Schmoele-Thoma, WC Gruber… - BMC pediatrics, 2013 - Springer
… administration of two recommended routine pediatric vaccines. Since fever is an important
issue with vaccine tolerability, we performed this open-label study on the efficacy and safety of …

… of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials

R Prymula, CA Siegrist, R Chlibek, H Zemlickova… - The Lancet, 2009 - thelancet.com
… recommended to allay concerns of high fever and febrile convulsion. We … at vaccination on
infant febrile reaction rates and vaccineFever is also a well described event after vaccination. …

[HTML][HTML] A randomized study of fever prophylaxis and the immunogenicity of routine pediatric vaccinations

J Wysocki, KJ Center, J Brzostek… - Vaccine, 2017 - Elsevier
… This paper reports results of a large, randomized, controlled, open-label trial examining
effects of coadministration or delayed administration (ie, dose timing) of paracetamol or …

[HTML][HTML] Immunogenicity and safety of fractional doses of yellow fever vaccines: a randomised, double-blind, non-inferiority trial

A Juan-Giner, D Kimathi, KH Grantz, M Hamaluba… - The Lancet, 2021 - thelancet.com
… -prequalified yellow fever vaccines for the general adult population and fills a crucial
knowledge gap to support WHO policy on the use of fractional dosing of yellow fever vaccine for …

The effect of antipyretics on immune response and fever following receipt of inactivated influenza vaccine in young children

EB Walter, CP Hornik, L Grohskopf, CE McGee… - Vaccine, 2017 - Elsevier
… also included an open label ibuprofen arm (3:3:2). The ibuprofen arm was smaller, as it
was added to obtain preliminary data on immunogenicity effects, and was open-label as the …

Immunogenicity, safety, and tolerability of a recombinant measles-vectored Lassa fever vaccine: a randomised, placebo-controlled, first-in-human trial

R Tschismarov, P Van Damme, C Germain, I De Coster… - The Lancet, 2023 - thelancet.com
… prevention of Lassa fever. To our knowledge, this study presents the first clinical data on a
Lassa fever vaccine candidate. We show that this measles-vector-based vaccine candidate (…

[HTML][HTML] … , double-blinded, controlled non-inferiority trials evaluating the immunogenicity and safety of fractional doses of Yellow Fever vaccines in Kenya and Uganda

D Kimathi, A Juan, P Bejon, RF Grais… - Wellcome Open …, 2019 - ncbi.nlm.nih.gov
fever vaccination as an off-label use in response to emergency situations where current
vaccinevaccine batch, the stock available and the suitability of injection devices. The minimal …

17DD yellow fever vaccine: a double blind, randomized clinical trial of immunogenicity and safety on a dose-response study

RM Martins, MLS Maia, RHG Farias… - Human vaccines & …, 2013 - Taylor & Francis
… In this study, 10 mo after yellow fever vaccination, only a small number of volunteers had
seroconverted to dengue, most probably due to the disease itself. Moreover, differences in …