Fine-mapping genetic associations

A Hutchinson, J Asimit, C Wallace - Human Molecular Genetics, 2020 - academic.oup.com
… The authors use simulations to demonstrate improved fine-mapping accuracy at pleiotropic
risk loci, compared to single-trait methods and ``Genetic analysis incorporating Pleiotropy …

[图书][B] Using heterogeneous stocks for fine-mapping genetically complex traits

LC Solberg Woods, AA Palmer - 2019 - Springer
… issues related to phenotyping, discuss genotyping methods relevant to these populations,
and describe statistical genetic analyses that are applicable to genetic analyses that use HS. …

Strategies for fine-mapping complex traits

SL Spain, JC Barrett - Human molecular genetics, 2015 - academic.oup.com
… all cell types in the human body using Cap Analysis of Gene Expression, which assays
RNA expression. This work provided maps of transcripts, TFs, promoters and enhancers that …

Genetic analysis and fine mapping of two genes for grain shape and weight in rice

L Guo, L Ma, H Jiang, D Zeng, J Hu… - Journal of integrative …, 2009 - Wiley Online Library
… Linkage analyses demonstrated that two genes controlling grain weight, designated as GW3
and GW6, were mapped to chromosome 3 and chromosome 6, respectively. Fine mapping

[HTML][HTML] Genetic analysis and gene fine mapping of aroma in rice (Oryza sativa L. Cyperales, Poaceae)

SX Sun, FY Gao, XJ Lu, XJ Wu, XD Wang… - Genetics and …, 2008 - SciELO Brasil
… In this paper we report the genetic analysis and fine mapping of aroma in rice variety
Chuanxiang-29B and provide a detailed analysis of its physical mapping based on the rice …

Genetic analysis and fine mapping of a rice brown planthopper (Nilaparvata lugens Stål) resistance gene bph19(t)

JW Chen, L Wang, XF Pang, QH Pan - Molecular Genetics and Genomics, 2006 - Springer
Genetic analysis and fine mapping of a resistance gene against brown planthopper (BPH)
biotype 2 in rice was performed using two F 2 populations derived from two crosses between …

Fine mapping and gene cloning in the post-NGS era: advances and prospects

D Jaganathan, A Bohra, M Thudi… - … and Applied Genetics, 2020 - Springer
… marker systems used for fine mapping and QTL cloning in … have improved trait analysis and
fine mapping. We opine that … were earlier used for fine mapping. A deeper understanding of …

Meta-analysis fine-mapping is often miscalibrated at single-variant resolution

M Kanai, R Elzur, W Zhou, KHH Wu, H Rasheed… - Cell genomics, 2022 - cell.com
… that call into question fine-mapping accuracy. These predicted … of fine-mapping improvement
in the GBMI meta-analyses … when interpreting fine-mapping results from meta-analysis of …

Fine mapping and candidate gene analysis of purple pericarp gene Pb in rice (Oryza sativa L.)

C Wang, Q Shu - Chinese science bulletin, 2007 - Springer
… In this study, we fine mapped the Pb gene using two F2 segregating … -pass mapping, the
Pb gene was located in the region downstream the SSR marker RM3820. In the fine mapping, …

From genome-wide associations to candidate causal variants by statistical fine-mapping

DJ Schaid, W Chen, NB Larson - Nature Reviews Genetics, 2018 - nature.com
… of fine-mapping, which in turn offer guidance for study designs. We review the use of genomic
annotation for fine-mapping, as well as the integration of gene … of the genetic basis of …