[HTML][HTML] Sequence analysis for detection of first-line drug resistance in Mycobacterium tuberculosis strains from a high-incidence setting

S Feuerriegel, B Oberhauser, AG George, F Dafae… - BMC microbiology, 2012 - Springer
… strains with known resistance patterns to first-line drugs from Sierra Leone (see Figure 1)
were sequenced in genes previously described to be involved in resistance development. …

[HTML][HTML] HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and …

RK Gupta, J Gregson, N Parkin… - The Lancet infectious …, 2018 - thelancet.com
… Our findings provide up-to-date estimates of the prevalence of HIV drug resistance in people
initiating or re-initiating first-line ART and we found worrying increases in prevalence in all …

Emergence of drug resistance in HIV type 1-infected patients after receipt of first-line highly active antiretroviral therapy: a systematic review of clinical trials

R Gupta, A Hill, AW Sawyer… - Clinical infectious …, 2008 - academic.oup.com
drug resistance is associated with increased mortality in patients who receive first-line HAART,
with NNRTI resistance … develop some form of genotypic drug resistance after 2 years, and …

Primary HIV drug resistance and efficacy of first-line antiretroviral therapy guided by resistance testing

M Oette, R Kaiser, M Däumer, R Petch… - JAIDS Journal of …, 2006 - journals.lww.com
… to assess the efficacy of first-line HAART guided by resistance testing. … of first-line HAART
guided by genotypic resistance testing by comparing treatment outcomes of patients with drug-…

Patterns of HIV-1 drug resistance after first-line antiretroviral therapy (ART) failure in 6 sub-Saharan African countries: implications for second-line ART strategies

, … African Studies to Evaluate Resistance  … - Clinical infectious …, 2012 - academic.oup.com
… may limit subsequent drug options and … drug resistance in individuals with prolonged first-line
ART failure, including complex nucleoside reverse transcriptase inhibitor (NRTI) resistance

Emergence of HIV drug resistance during first-and second-line antiretroviral therapy in resource-limited settings

MC Hosseinipour, RK Gupta, G Van Zyl… - The Journal of …, 2013 - academic.oup.com
… Collaborative HIV and Drug Resistance Network workshop in … the emergence of first-line drug
resistance mutations after 12 … to second-line therapy and summarize HIV resistance among …

Molecular detection of mutations associated with first-and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium …

PJ Campbell, GP Morlock, RD Sikes… - Antimicrobial agents …, 2011 - Am Soc Microbiol
… associated with drug resistance to rapidly and accurately determine the drug susceptibility
… study were not associated with drug resistance. Each resistance-associated locus examined …

[HTML][HTML] Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study

J Gregson, M Tang, N Ndembi, RL Hamers… - The Lancet infectious …, 2016 - thelancet.com
drug resistance in regions hardest hit by the HIV pandemic. We aimed to do a global
assessment of drug resistance after virological failure with first-line tenofovir-containing ART. …

The impact of transmitted drug resistance on the natural history of HIV infection and response to first-line therapy

CASCADE Virology Collaboration - Aids, 2006 - journals.lww.com
… We describe, for the first time, the impact of transmitted HIV-1 drug resistance on the CD4
cell count decline up to 5 years following HIV seroconversion. Although no difference has been …

Effect of pretreatment HIV-1 drug resistance on immunological, virological, and drug-resistance outcomes of first-line antiretroviral treatment in sub-Saharan Africa: a …

RL Hamers, R Schuurman, KCE Sigaloff… - The Lancet infectious …, 2012 - thelancet.com
… We used the International Antiviral Society-USA drug resistance mutation list and the … drug
resistance categories: no pretreatment drug resistance, pretreatment drug resistance with fully …