… , has recently been investigated and shown to be relevant to the cardiovascular system (Ong
et al.… and fission proteins as novel therapeutic targets for combating cardiovascular disease. …

… fusion and fission proteins as novel targets for treating cardiovascular disease. … cytosol to
the OMM where it interacts with other proteins of the fission machinery including human fission …

… mitochondrial fission mediated by dynamin-1-like protein (… fission in cardiovascular disease
progression and emerging therapeutic strategies to restrict fission-induced cardiovascular …

… cycles of fusion and fission to modulate their morphology, … protein 1 (Drp1) is known as the
major pro-fission protein … pathophysiology underlying various cardiovascular diseases (CVDs)…

… fission proteins and provide clarity about how Drp1 is connected to adaptor proteins in the
dynamic fission … Drp1-mediated fission protein networking and its regulatory role in fission and …

… Because Drp1 does not have a transmembrane domain, for it to bind to the OMM, it either
binds directly to mitochondrial fission protein 1 (Fis1) 10 or induces fission independently of …

… mitochondrial fission and fusion to treat cardiac diseases. The … proteins involved in
physiological mitochondrial fission (ie., Mff… by targeting Drp1-Fis1 protein/protein interaction, …

… In physiological conditions, mitochondria continuously undergo cycles of fusion and fission,
and various proteins have been found to regulate these processes and will be discussed in …

… in cardiac mitochondrial fission or fusion proteins should help … dynamics in cardiovascular
health and disease should result … for treating patients with cardiovascular disease, the leading …

… a protein that plays a critical role in the development of several cardiovascular diseases,
controls fission, … Many cardiovascular diseases, including pulmonary arterial hypertension, heart …