… Moreover, it is unclear how FKBP5 deletion affects other glucocorticoid-dependent … SNPs
in the FKBP5 gene. Here, we show that FKBP51-mediated impairment in stress resiliency and …

… response may underlie the stress resilient behavior observed in the Fkbp5 deficient mice. …
stress resilience associated genes through gene co-expression network analysis in Fkbp5 …

… methylation of stress genes NR3C1 and FKBP5 with the posttrauma responses of PTSD,
PTG, and resilience. Overall, methylation of different regions of both NR3C1 and FKBP5 were …

… -feedback neural interface that could help us understand risk and resilience mechanisms to
… that the absence of FKBP5 main effects with evidence of gene by early stress interactions is …

… Compared with wild-type mice, Fkbp5 KOs generally exhibit a more resilient phenotype,
characterized by lower corticosterone levels and improved sleep architecture and behavioral …

… glucocorticoid concentrations, we propose that FKBP5 is a major mediator of … stress
resilience, because it would allow finer tuning of the HPA axis to adversity. Studies using FKBP5 …

… stress coping, stress resilience, and homeostasis. The FK506-binding immunophilins FKBP4
and FKBP5 … FKBP4 contributes to the negative feedback of glucocorticoids, whereas FKBP5 …

… For example, mice lacking the Fkbp5 gene show stress-induced decline in synapsin … Fkbp5
silencing in the amygdala was shown to confer resilience to restraint stress exposure [32]. …

… GR activity also stimulates Fkbp5 gene transcription [100,101], the higher FKBP5 levels in …
target genes. In fact, Fkbp4 contributes to the negative feedback of glucocorticoids, and Fkbp5 …

… 5 (FKBP5) gene may interact with childhood abuse to increase risk of developing posttraumatic
stress … the relationship of four previously identified FKBP5 putative risk SNPs (rs9296158, …