… the 5 -flanking region. To elucidate whether these polymorphisms affect the expression of
apo(a), we measured plasma Lp(a) concentrations in vivo by ELISA and examined expression …

We have isolated and characterized a 2.5-kilobase pairs genomic DNA fragment which includes
the 5′-flanking region and the first and second exons of the human apolipoprotein (apo…

… the cDNA for a new protein, apolipoprotein L (apoL), present … Project and three expressed
sequence tag sequences, we … homology with previously described apolipoproteins. The genes …

… Extensive size variation of the apo[a] gene results in the expression of apo[a] isoforms with
variable numbers of tandemly repeated kringle domains ranging from 11 to more than 50 (4-6)…

… of its mRNA, which distinguishes it from all the other human apolipoprotein genes whose …
or in any other human apolipoprotein. Optimal alignments of the 5′ flanking regions of the rat …

… This region of the apolipoprotein(a) gene contains … in this region account for some of the
variation in plasma Lp(a) concentration. Transgenic mice expressing human apolipoprotein(a) …

… in the coding regions but also in the non-coding and intron regions. The mouse and the
human apolipoprotein E genes were homologous in the 5' proximal flanking region up to about …

… apolipoproteins … ”flanking sequence (20). In the present study we attempted to define DNA
elements within the apoE gene and its flanking sequence that promote its transient expression …

… region suggested that nucleotides −821 and −685 are needed for maximum expression of
apo … been shown to be active in regulating apo C-III expression. The transcription factor NF-κB …

… apolipoprotein E gene using a transient expression … flanking region of the human
apolipoprotein E gene was capable of directing chloramphenicol acetyltransferase gene expression …