[HTML][HTML] Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration

E Kersten, CC Paun, RL Schellevis, CB Hoyng… - survey of …, 2018 - Elsevier
… For each compound, we provide a short description of its … In summary, compounds belonging
to the oxidative stress … on systemic and ocular fluid compounds as potential biomarkers in …

Agents for the prevention and treatment of age-related macular degeneration and macular edema: a literature and patent review

CT Supuran - Expert Opinion on Therapeutic Patents, 2019 - Taylor & Francis
… of fluid from the blood vessels with the consequent edema formation [Citation15,Citation16].
Similar to macular degeneration, … The compound is used as a photosensitizer for PDT, as by …

[HTML][HTML] Metabolomics and age-related macular degeneration

CN Brown, BD Green, RB Thompson, AI Den Hollander… - Metabolites, 2018 - mdpi.com
Age-related macular degeneration (AMD) leads to irreversible visual loss, therefore, early
intervention is desirable, but due to its multifactorial nature, diagnosis of early disease might …

[HTML][HTML] Metabolomics in age-related macular degeneration: a systematic review

XW Hou, Y Wang, CW Pan - Investigative ophthalmology & …, 2020 - iovs.arvojournals.org
Purpose: Age-related macular degeneration (AMD) is one of the leading causes of blindness
among the elderly, and the exact pathogenesis of the AMD remains unclear. The purpose …

[HTML][HTML] Therapeutic approaches for age-related macular degeneration

RM Galindo-Camacho, C Blanco-Llamero… - International journal of …, 2022 - mdpi.com
… In recent years, several synthetic and natural active compounds have been proposed as …
Neovascular AMD incorporates some typical lesions, such as the presence of fluid or retinal …

[PDF][PDF] Diabetic macular edema, retinopathy and age-related macular degeneration as inflammatory conditions

UN Das - Archives of Medical Science, 2016 - termedia.pl
… and age-related macular degeneration Macular edema occurs when fluid and protein deposits
… Even EPA may form compounds similar to those that are formed from AA as shown here …

Metabolomic profiling of the aqueous humor in patients with wet age-related macular degeneration using UHPLC–MS/MS

G Han, P Wei, M He, H Teng, Y Chu - Journal of proteome …, 2020 - ACS Publications
degenerative disease, is becoming a leading cause of … vision loss in patients with macular
degeneration. (3) The … and unknown metabolites in complex biological fluids, tissues, and cells…

Discovery of oral VEGFR-2 inhibitors with prolonged ocular retention that are efficacious in models of wet age-related macular degeneration

EL Meredith, N Mainolfi, S Poor, Y Qiu… - Journal of Medicinal …, 2015 - ACS Publications
fluid and blood. This leads to retinal edema, scar tissue formation, and irreversible damage
to the macula. The … To achieve our objective of identifying compounds with preferential ocular …

Review of nutrient actions on age-related macular degeneration

S Zampatti, F Ricci, A Cusumano, LT Marsella… - Nutrition research, 2014 - Elsevier
… The actions of nutrients and related compounds on age-related macular degeneration (AMD…
(CNV) with subsequent fluid leakage and major degeneration of RPE and photoreceptors. In …

Age-related macular degeneration: experimental and emerging treatments

JP Hubschman, S Reddy, SD Schwartz - Clinical Ophthalmology, 2009 - Taylor & Francis
… , which showed that oral administration of this compound is potentially beneficial in treating
CNV … This allows the treating ophthalmologist to detect small lesions with sub-retinal fluid that …