… Although further measurements in vivo are necessary to confirm and to provide a more
detailed knowledge of the optimal fluorescence-derived parameters for distinguishing tumor from …

… tissue samples near the tumor margin from fluorescent and non-fluorescent areas for …
tumor from healthy brain tissue. Others measured the fluorescent signal intensity from tumor and …

… the red fluorescent tumor under the fluorescence microscope (16). The use of 5-ALA for
intraoperative monitoring in high-grade glioma … Chemical structure and fluorescence analysis of …

… The objective of this work is the histological characterization of peripheral tumor cells in the
border zone of GBM shown in 5-ala-guided surgery, including proliferative activity and nestin …

… GBM and significantly prolonged their tumor-free survival [5]. FIGR was approved in the
European Union and its use expanded worldwide. It was envisaged that FIGR would undergo …

… As a second model for primary brain tumor, we chose the glioblastoma cell line Gli36
expressing GFP. As shown in Figure 6B, CLIO-Cy5.5 colocalized with the GFP fluorescence …

… Our results showed intra-operative fluorescence allowed guided intracranial GBM
resection that could be validated by simultaneous 5-ALA imaging. The combination of post-operative …

… glioma cell lines, solid tumor, and invasive tumor cells in an experimental mouse glioma model
and human glioma … we have analyzed the fluorescent lifetime of the fluorescent signal as …

… Given the possible confounding effect of an inflammaa tory response in the xenograft
glioma model at the site of tumor implantation, we proceeded to test fluorescein biodistribution …

… potential diagnosis of brain tumors. We evaluate whether the fluorescence lifetime contrast
can be achieved between normal brain and brain tumor (glioblastoma) areas as identified …