过去一年中添加的文章,按日期排序

Identification of Plant Peroxidases Catalyzing the Degradation of Fluorinated Aromatics Using a Peroxidase Library Approach

A Ware, S Hess, D Gligor, S Numer… - Engineering in Life …, 2024 - Wiley Online Library
13 天前 - … has been shown to catalyze 4-fluorophenol (4FP) defluorination [30]. It was noted
in this study that inactivation of the enzyme was observed, which could be a limitation for its …

Defluorination of Organofluorine Compounds Using Dehalogenase Enzymes from Delftia acidovorans (D4B)

S Farajollahi, NV Lombardo, MD Crenshaw, HB Guo… - ACS …, 2024 - ACS Publications
99 天前 - … shown to grow in the presence of perfluorinated compounds. Of these enzymes,
two demonstrated the ability to defluorinate small, fluorinated compounds, including one with a …

[HTML][HTML] Defluorination of monofluorinated alkane by Rhodococcus sp. NJF-7 isolated from soil

M Yan, Z Gao, X Xiang, Q Wang, X Song, Y Wu… - AMB Express, 2024 - Springer
117 天前 - defluorination, affecting fluoride toxicity in cells and altering the stoichiometric
conversion of fluorinated compounds to fluoride through enzymatic … of bacterial defluorination

Co-Removal of Perfluorooctanoic Acid and Nitrate from Water by Coupling Pd Catalysis with Enzymatic Biotransformation

M Long, CW Zheng, MA Roldan, C Zhou… - Environmental …, 2024 - ACS Publications
137 天前 - perfluorinated compounds. (9) However, certain microorganisms are reported to be
capable of mineralizing less-fluorinated compounds … be defluorinated to less fluorinated or …

Toward the development of a molecular toolkit for the microbial remediation of per-and polyfluoroalkyl substances

M Hu, C Scott - Applied and Environmental Microbiology, 2024 - Am Soc Microbiol
201 天前 - … C 8 ) unsaturated fluorinated compounds by KB1 under the … defluorination of
fluorinated compounds (107). To date, the identities of the enzymes responsible for defluorination

Abstract 2259 PFAS Are Not Forever: Enzymes and Evolution Rise to the Challenge

L Wackett - Journal of Biological Chemistry, 2024 - ASBMB
214 天前 - … remediation of fluorinated compounds known as per- and … defluorinating enzymes,
engineered microbial systems for defluorination, and evolved higher levels of defluorination. …

Enzymatic defluorination of a terminally monofluorinated pentyl moiety: oxidative or hydrolytic mechanism?

B Haschimi, F Willecke, S Mundinger, W Hüttel… - Drug Metabolism and …, 2024 - ASPET
217 天前 - … , fluorinated compounds play an important role in drug development. In medicinal
chemistry, isosteric substitution of hydrogen with fluorine is … shown that fluorination cannot be …

Microwell fluoride assay screening for enzymatic defluorination.

LP Wackett - Methods in Enzymology, 2024 - europepmc.org
263 天前 - … There is intense interest in removing fluorinated compounds from the environment,
enzymes, and defluorinating enzymes are readily monitored by fluoride determination. …

Recombinant Pseudomonas growing on non-natural fluorinated substrates shows stress but overall tolerance to cytoplasmically released fluoride anion

AG Dodge, CJ Thoma, MR O'Connor, LP Wackett - Mbio, 2024 - Am Soc Microbiol
298 天前 - … active defluorinating enzyme, (ii) express the enzyme in a … fluoride release,
and (iv) determine what level of fluoride … The Delftia enzyme defluorinated α-fluorophenylacetic …

Towards covalent fibroplast activation protein (FAP) inhibitors for delivery of therapeutic radionuclides into FAP-positive tumors

S Humpert, B Zlatopolskiy, AL Elsner… - 25th International …, 2023 - juser.fz-juelich.de
300 天前 - … To thisend, [18F]fluoride was loaded onto a QMA anion … pH (7.4), and rapid
defluorination in blood serum, with ahalf-… of the warhead to theFAP enzyme could not be examined …