Defluorination of 4-fluorothreonine by threonine deaminase

L Wu, H Deng - Organic & Biomolecular Chemistry, 2020 - pubs.rsc.org
fluorination enzyme, fluorinase, the first committed enzyme in fluorometabolism. Later on,
genome mining revealed several other putative fluorometabolite-producing strains including …

Defluorination of Organofluorine Sulfur Compounds by Pseudomonas Sp. Strain D2

BD Key, RD Howell, CS Criddle - Environmental science & …, 1998 - ACS Publications
defluorination of fluorinated sulfonates, a linkage between sulfur assimilation and defluorination,
and generation of volatile fluorinated … of the specific nature of the enzyme(s) and cofactor…

Unexpected mechanism of biodegradation and defluorination of 2, 2-difluoro-1, 3-benzodioxole by Pseudomonas putida F1

MD Bygd, KG Aukema, JE Richman, LP Wackett - MBio, 2021 - Am Soc Microbiol
… here a novel mechanism underlying fluoride displacement from the DFBD group. It was
demonstrated that the only enzyme required for defluorination of DFBD is toluene dioxygenase, …

Enzymatic carbon-fluorine bond cleavage by human gut microbes

SI Probst, FD Felder, V Poltorak, R Mewalal, IK Blaby… - bioRxiv, 2024 - biorxiv.org
defluorinating and 381 non-defluorinating enzymes 382 … to differentiate defluorinating and
non-defluorinating enzymes, … that the defluorinating and non-defluorinating enzymes did not …

Microbial degradation of fluorinated drugs: biochemical pathways, impacts on the environment and potential applications

CD Murphy - Applied microbiology and biotechnology, 2016 - Springer
… microbial biotransformation will also enable the discovery of novel enzyme activities that
may have potential as industrial biocatalysts for the production of new fluorinated compounds. …

[HTML][HTML] Harnessing fluoroacetate dehalogenase for defluorination of fluorocarboxylic acids: in silico and in vitro approach

Y Li, Y Yue, H Zhang, Z Yang, H Wang, S Tian… - Environment …, 2019 - Elsevier
… Despite of the key role played in chemical industries, the fluorinated compounds, especially
… strongly demonstrate the efficient defluorination of 2-fluoropropionic acid by enzyme FAcD. …

Aerobic biotransformation and defluorination of fluoroalkylether substances (ether PFAS): substrate specificity, pathways, and applications

B Jin, Y Zhu, W Zhao, Z Liu, S Che… - … science & technology …, 2023 - ACS Publications
… treatment and demonstrated enhanced defluorination for several perfluorinated ether PFAS,
… the defluorinating routes by identifying the microorganisms and enzymes responsible for the …

Enzymatic Degradation of PFAS: Current Status and Ongoing Challenges

BA Harris, J Zhou, BO Clarke, IKH Leung - ChemSusChem - Wiley Online Library
enzymes capable of efficiently breaking one CF bond, let alone those that can completely
defluorinate fully fluorinated … unlikely we will discover natural enzymes that have potential to be …

Enzymatic fluorination using fluoride ion generated from degradation of fluorinated materials

N Iwai, Y Tsuboki, M Kitazume, T Kitazume - Journal of Fluorine Chemistry, 2010 - Elsevier
… In the fluorine science, the recycle of fluorinefluorinated materials are most stable
compounds in the environment, nature seems to be reluctant to develop biological defluorination

Degradation and transformation of organic fluorine compounds

AH Neilson, AS Allard - Organofluorines, 2002 - Springer
enzyme inactivation is illustrated for both microbial and a few mammalian enzymes.A …
degradation of a range of fluorinated sulfones [116], and defluorination was observed with di…