Natural production of fluorinated compounds and biotechnological prospects of the fluorinase enzyme
MF Carvalho, RS Oliveira - Critical reviews in biotechnology, 2017 - Taylor & Francis
… and rocks, though their concentrations and production mechanisms are not well known. This
… about fluorinated compounds with natural origin. The paucity of these compounds and the …
… about fluorinated compounds with natural origin. The paucity of these compounds and the …
Natural and engineered biosynthesis of fluorinated natural products
MC Walker, MCY Chang - Chemical Society Reviews, 2014 - pubs.rsc.org
… bioactive compounds but our ability to produce site-selectively fluorinated natural products
… and current methods for fluorination. Living systems provide an alternative route to chemical …
… and current methods for fluorination. Living systems provide an alternative route to chemical …
[HTML][HTML] Enzymatic synthesis of fluorinated compounds
X Cheng, L Ma - Applied Microbiology and Biotechnology, 2021 - Springer
… of which are fluorinated natural products of various structures. However, there are still very
… fluorinated natural products found in nature. The main known fluorinated natural products in …
… fluorinated natural products found in nature. The main known fluorinated natural products in …
Fluorinated natural products: Occurrence and biosynthesis
… the participation of fluorine in biochemical processes is the … precludes incorporation of
fluorine into natural products by the … which organohalogen compounds are formed in nature [5]. …
fluorine into natural products by the … which organohalogen compounds are formed in nature [5]. …
The rare fluorinated natural products and biotechnological prospects for fluorine enzymology
KKJ Chan, D O'Hagan - Methods in enzymology, 2012 - Elsevier
… The known fluorinated natural products. Fluoroacetate is found in many plants and in one
bacterium (Streptomyces cattleya). Fluoroacetate is toxic because it is converted to (2R,3R)-2-…
bacterium (Streptomyces cattleya). Fluoroacetate is toxic because it is converted to (2R,3R)-2-…
Fluorine-containing natural products
D O'Hagan, DB Harper - Journal of Fluorine Chemistry, 1999 - Elsevier
… In this article we review the fluorinated natural products and … fluorinated natural products
have been isolated excluding the fatty acid homologues [3]. The first organo-fluorine compound …
have been isolated excluding the fatty acid homologues [3]. The first organo-fluorine compound …
The fluorinated natural products
D áO'Hagan - Natural product reports, 1994 - pubs.rsc.org
… effective method for studying the metabolism of fluorinated compounds, and with the dramatic
… , the technique is an attractive tool with which to screen for novel fluorinated metabolites. …
… , the technique is an attractive tool with which to screen for novel fluorinated metabolites. …
Fluorinated natural products: the biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya
… for introducing fluorine into organic compounds … produced fluorinated compounds and focus
on the work that has been done to elucidate the biochemistry of fluorometabolite production …
on the work that has been done to elucidate the biochemistry of fluorometabolite production …
The natural production of chlorinated compounds
GW Gribble - Environmental science & technology, 1994 - ACS Publications
… Not only are naturally occurring organohalogen compounds … several fluorine-containing
natural products exist (4), the presentreview focuses principally on organochlorine compounds. …
natural products exist (4), the presentreview focuses principally on organochlorine compounds. …
Synthetic biology approaches to fluorinated polyketides
BW Thuronyi, MCY Chang - Accounts of chemical research, 2015 - ACS Publications
… fluorine into complex natural products by engineering biosynthetic machinery to incorporate
fluorinated … select for fluorinated compounds, we have studied one of the only characterized …
fluorinated … select for fluorinated compounds, we have studied one of the only characterized …
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