… but hampered by design limitations and small sample sizes. Future evaluation should be
encouraged within formal prospective clinical trials that include clear eligibility criteria, full …

… studies on primary focal therapy for localised prostate cancer … , the study had several
limitations. The attrition rate in the … to undergo radical therapy without a clear clinical indication, …

… PCa are eligible for focal treatment; … focal retreatment rates of ≤20% should be considered
clinically acceptable but subsequent whole-gland therapy deemed a failure of focal therapy. …

… Authors of included studies were contacted when one of the outcomes was not clearly or …
been regarded as a major limitation in the whole rationale for focal therapy in PCa. Several …

… fibers are clearly apparent. … limitations of both consensus panels, the process itself was
helpful in refining some of the conceptual and practical considerations that relate to focal therapy …

… focal therapy and how the efficacy of focal therapy should be assessed. This review articles
discusses the current status of focal therapy, … A limitation of including intermediate- and high-…

… effectiveness, that is with the limits set by the most difficult … therapy may be reluctant to suggest
group and focal therapy … the suggestion of focal therapy, clearly wanting longer personal …

… In this paper, we will outline the limitations and cons of these … These data clearly show that
definitive conventional therapy … The main limitation for the concept of focal therapy in PCa is …

… unifocal treatment, while limitations in imaging can preclude … clear results associated with
focal therapy and the difficulties in detecting all cancerous areas of the prostate, focal therapy …

… Results and limitations Inclusion criteria for candidates in focal therapy trials are patients with
… needs mature oncologic follow-up data and thus needs standardisation, clear definitions of …