Tumor focality in prostate cancer: implications for focal therapy

M Karavitakis, HU Ahmed, PD Abel, S Hazell… - Nature reviews Clinical …, 2011 - nature.com
Focal therapy is widely used for the treatment of breast 2 and kidney 3 cancer, and can …
rates than whole-gland therapy; however, data on focal therapy for prostate cancer are limited. …

Evaluating localized prostate cancer and identifying candidates for focal therapy

AO Sartor, H Hricak, TM Wheeler, J Coleman… - Urology, 2008 - Elsevier
cancers can … prostate cancer being considered for focal therapy by providing additional
evidence that the patient does not harbor an otherwise undetected high-risk, aggressive cancer. …

[HTML][HTML] Focal therapy for prostate cancer: rationale and treatment opportunities

V Kasivisvanathan, M Emberton, HU Ahmed - Clinical Oncology, 2013 - Elsevier
… TPM still remains necessary before selecting suitable candidates for focal therapy, although
… of MP-MRI in the detection of clinically significant prostate cancer. Guiding Focal Therapy

Focal therapy in prostate cancer: international multidisciplinary consensus on trial design

W Van Den Bos, BG Muller, H Ahmed, CH Bangma… - European urology, 2014 - Elsevier
Focal therapy has been introduced for the treatment of localised prostate cancer (PCa).
To provide the necessary data for consistent assessment, all focal therapy trials should be …

Will focal therapy become a standard of care for men with localized prostate cancer?

HU Ahmed, D Pendse, R Illing, C Allen… - Nature clinical practice …, 2007 - nature.com
… Radical therapy is associated with considerable … cancer control. The arguments for and
against active surveillance and radical therapy are reviewed in this article, with focal therapy

Focal therapy for localised unifocal and multifocal prostate cancer: a prospective development study

HU Ahmed, RG Hindley, L Dickinson… - The lancet …, 2012 - thelancet.com
Focal therapy of individual prostate cancer lesions, whether multifocal or unifocal, leads to
a … -effects and an encouraging rate of early absence of clinically significant prostate cancer. …

[HTML][HTML] An updated systematic review on focal therapy in localized prostate cancer: what has changed over the past 5 years?

JS Hopstaken, JGR Bomers, MJP Sedelaar, M Valerio… - European Urology, 2022 - Elsevier
Focal therapy is a promising, minimally invasive strategy to selectively treat localized prostate
cancer. … the effectiveness of focal therapy in patients with localized prostate cancer in terms …

Morbidity of focal therapy in the treatment of localized prostate cancer

E Barret, Y Ahallal, R Sanchez-Salas, M Galiano… - European urology, 2013 - Elsevier
Focal therapy (FT) for prostate cancer (PCa) seems to be part of a natural evolution in the …
Focal therapy (FT) has emerged as a middle ground between AS and radical therapy, …

[HTML][HTML] Focal therapy for prostate cancer: complications and their treatment

A Rakauskas, G Marra, I Heidegger… - Frontiers in …, 2021 - frontiersin.org
… The oncological effectiveness of focal therapy is yet to be proven in long-term robust trials. …
after focal therapy. When compared to whole gland treatments, focal therapy provides a …

Can we deliver randomized trials of focal therapy in prostate cancer?

…, Prostate Cancer RCT Consensus Group - Nature reviews Clinical …, 2014 - nature.com
focal therapy, in men with localized prostate cancer with discussions of the key issues on
trial design. The meeting was supported by a research grant provided by the Medical Research …