Trends in reporting drug-associated liver injuries in Taiwan: a focus on amiodarone

JH Ye, YF Ho, AWF On, WW Chen, YM Huang… - International journal of …, 2018 - Springer
liver injury and to delineate critical factors for suspected drug-related hepatotoxicity with a
focus on reports associated with amiodarone… reports associated with liver injury. Information on …

Dronedarone, amiodarone and other antiarrhythmic drugs, and acute liver injuries: a case-referent study

L Grimaldi-Bensouda, H Wedemeyer, J Wiegand… - International Journal of …, 2018 - Elsevier
Background Spontaneous reports of acute liver injuries (ALI) in patients taking dronedarone
triggered an EMA alert in 2011. This study aimed to assess the risk of ALI for class III …

Amiodarone hepatotoxicity

M Babatin, SS Lee, PT Pollak - Current vascular pharmacology, 2008 - ingentaconnect.com
… Further evidence against acute liver injury related to intravenous amiodarone, is the fact that
… later exposure to oral amiodarone [60]. Clinically apparent severe liver disease has been …

Chronic liver injury induced by drugs and toxins

A Ortega‐Alonso, RJ Andrade - Journal of Digestive Diseases, 2018 - Wiley Online Library
… , and some drugs such as amiodarone or methotrexate have been frequently implicated in
… data on chronicity in DILI with a particular focus on the epidemiology, mechanisms and risk …

[HTML][HTML] N-acetylcysteine treats intravenous amiodarone induced liver injury

ML Mudalel, KP Dave, JP Hummel… - World Journal of …, 2015 - ncbi.nlm.nih.gov
… ) amiodarone drug induced liver injury (DILI). The patient received IV N-acetylcysteine (NAC)
which resulted in a rapid improvement in liver … Using a rat model, their research focused on …

Amiodarone hepatotoxicity with absent phospholipidosis and steatosis: a case report and review of amiodarone toxicity in various organs

A Cimic, J Sirintrapun - Case reports in pathology, 2013 - Wiley Online Library
… (amiodarone-) induced liver injury without phospholipidosis or steatosis. In doing so, we will
also review the literature on the morphology of amiodarone … this by focusing attention during …

[PDF][PDF] Fatal acute liver failure after intravenous amiodarone administration

JG Li, TC Yang, DM Yu, TH Ren - J Formos Med Assoc, 2015 - core.ac.uk
… In general, liver injury is rapidly reversible after discontinuation of amiodarone and the fatality
rate is low. As … Future studies should focus on the underlying mechanisms for intravenous …

[HTML][HTML] Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy

CW Lin, YS Chen, CC Lin, YJ Chen, GH Lo, PH Lee… - Scientific Reports, 2015 - nature.com
… with amiodaroneliver injury in the early phase of liver regeneration following PHx.
However, both Caspase-3 cleavage and Caspase-8 cleavage were slightly lower in amiodarone-…

Amiodarone hepatotoxicity: prevalence and clinicopathologic correlations among 104 patients

JH Lewis, RC Ranard, A Caruso, LK Jackson… - Hepatology, 1989 - journals.lww.com
… Although the most commonly reported serious adverse effect has been pulmonary toxicity
(2-4, 6, 7, 11-16), increasing attention has been focused on hepatic injury. Elevated blood …

Drug-induced liver injury: highlights of the recent literature

M Real, MS Barnhill, C Higley, J Rosenberg, JH Lewis - Drug safety, 2019 - Springer
… [87] conducted a meta-analysis of 27 clinical trials focusing on potential liver injury associated
… Although amiodarone-induced liver injury (AILI) has been extensively documented, less is …