… receptor is confined to the apical surface of the epithelium that is out of direct contact with
folate and any folate receptor-… as a salvage receptor to retrieve and prevent loss of folate in the …

… can identify patients with receptors overexpressed on the surface of cancer cells, thus …
patients for personalized treatment with a desirable targeted therapeutic. The folate receptor (FR) …

… One potential target is the alpha isoform of the folate receptor (FR), which … cancer and
nonsmall-cell lung cancer (NSCLC). In this review, we discuss the concept of personalized cancer …

… a Folate can be transported into the cell by three different proteins: the folate receptor (FR)
(panel A), the reduced folate carrier (RFC) (panel B), and the proton-coupled folate …

… death; meanwhile, the folate receptors are recycled back to the surface of the cell to engage
in further rounds of drug internalisation. The availability of unoccupied receptors on the cell …

… exploiting FRα in the diagnosis and treatment of patients with cancer. … , folate-based drug
conjugates could also bind to FRβ, which could merit further exploration as a cancer treatment …

… folate uptake from serum8 or by generating regulatory signals.4, 9 This review summarizes
folate's role in cancer, compares folate … and progression of epithelial cancers, as well as its …

… The concept of treating cancer with the patient's own immune system was first introduced by
… immune system in cancer treatment, Coley began to treat cancer patients with intratumoral …

… two folate conjugated gold nanoparticles for cancer treatment Citation13. The group actively
targeted a gold nanosphere for use in the heat alabation of folate receptor–positive cancer …

… the most gynecological cancer-related deaths. The development of new treatment options is
… The frequent overexpression of folate receptor α (FRα) in ovarian cancer has provided the …