… In summary, it is necessary to consider not only the folate or vitamin B12 status that causes
signs and symptoms of deficiency but also the concept of increased risk of NTDaffected births…

… Iron, vitamin B 12 and folate are required for essential metabolic functions. Deficiency states
… Investigation of suspected iron, vitamin B 12 or folate deficiency should first be directed at …

… The interrelationship between vitamin B 12 and folate metabolism in man is best illustrated
… from a deficiency of either vitamin. Large pharmacological doses of either vitamin will elicit a …

… Folate is a water-soluble B-vitamin and enzymatic cofactor that is necessary for the …
Impairment of folate-mediated one-carbon metabolic pathways can result from B-vitamin deficiencies …

… of folate and vitamin BIZ is intimately connected, and this is reflected in the fact that a deficiency
of either vitamin may … There is evidence to show that a block in folate metabolism is the …

… The vitamins folic acid, B12 and B6 and B2 are the source of … or inadequate status of these
vitamins. Homocysteine, a product … relationship between inadequate folate status and cancer. …

… of vitamin B 12 and folate deficiency. The most common explanations for poor vitamin B 12
status are a low dietary intake of the vitamin (… ) are at risk for vitamin B 12 deficiency, evidence …

… The detection and correction of folate deficiency prevents megaloblastic anaemia and …
folate and vitamin B 12 are associated with cognitive decline, depression and neuropathy. Folate …

… plasma concentration of vitamin B12 is greater … of folate (ie >400 μg/day) and vitamin B12
(ie >2 μg/day) depending on an individual's capacity to absorb and metabolise these vitamins …

… Because plasma folate is typically measured in the same assay as plasma vitamin B12, our
laboratory has made simultaneous measures of plasma vitamin B12 and folate in Guatemala…