… cells. Here we report that the magnitude of the Tfh cell response was dictated by the amount
of antigen and directly correlated with the magnitude of the GC B cell response. In addition, …

… LCMV-specific antibodies that keep viral … antibodies, we show that sustained activity of
T FH cells promotes control of the chronic infection in face of exhausted CD8 T cell responses…

… -specific CD4 T cells that caused up-regulation of the transcription factor Bcl6 and enhanced
T follicular helper cell responses at late, but not early, stages of chronic viral infection. This …

… Effective humoral immunity depends on the support of B cell responses by T follicular helper
(Tfh) cells. Although it has been proposed that Tfh cell differentiation requires TB interactions…

… that T follicular helper cells (Tfh) specialize in providing cognate help to B cells and are
fundamentally required for the generation of T cell–dependent B cell responses. Perturbations in …

… that the prolonged antigenic stimulation during viral persistence drives a specific CD4 T cell
… Yet, the CD4 T cell response generated during a persistent infection is not merely a delayed …

… Among memory T helper cells, T follicular helper (T FH ) cells have been considered as a
distinct subset due to their unique ability to promote B cell responses and antibody affinity …

… B cells and induce IgG2a antibodies (in mice) but in larger amounts inhibits B cell responses…
In the absence of T cell–expressed BCL6, B cell responses to protein antigens do not occur …

… T follicular helper cells (TFH) are of critical importance for humoral immune responses [1]. …
quickly readopt their B-cell helper phenotype, we tested their response after rechallenge with …

… The importance of this molecule for B cell responses is demonstrated by mice lacking CD40
or CD40L, which display abortive B cell responses and a failure to generate GCs and long-…