… initiation and in selection of first-line agents. Ardeshna et al. have … since its development in
the late 1990s. When compared to … first-line immunochemotherapy for follicular lymphoma: a …

Disease overview Follicular lymphoma (FL) is generally an indolent B cell lymphoproliferative
disorder of transformed follicular center B cells. Follicular lymphoma is characterized by …

… was associated with inferior survival following first-line treatment. The reduced survival we
observed after second-line and later therapy supports the development of new treatments for …

… Effectiveness of first-line management strategies for stage I follicular lymphoma: analysis
of … CVP as first-line treatment for advanced follicular lymphoma. Blood 2005; 105: 1417–1423. …

… with newly diagnosed follicular lymphoma from 2004 to 2007 … with de novo stage I follicular
lymphoma. Less than one third … of patients with stage I follicular lymphoma treated with these …

… Thus, the GC B cells must accumulate further oncogenic hits during the later phases of B …
However, several lines of evidence have also demonstrated a pivotal role for some of those (…

… To inform clinical research efforts with an expert practice-based scenario including patient
characteristics and outcomes in the third-line setting or later, we developed the Lymphoma …

… Recent discoveries have identified patients at high risk for poor outcomes to first-line therapy
(m7–Follicular Lymphoma International Prognostic Index [m7-FLIPI]) and for poor outcomes …

… with follicular lymphoma. (A) Treatment options for patients who did not receive
immunochemotherapy in the first line. (B) … , which can be useful in later lines, specifically if …

… of follicular lymphoma patients to DLBCL in later lines … -line or later therapy secondary to
advancing age, cumulative treatment-associated toxicity, the transformation of their lymphoma …