The abscopal effect of stereotactic radiotherapy and immunotherapy: Fool's gold or El Dorado?

D Xing, S Siva, GG Hanna - Clinical oncology, 2019 - Elsevier
… The optimal radiation dose and fractionation for enhancing the abscopal effect or the … three
fractions is the optimal dose to induce the abscopal effect in vivo. By contrast, Filatenkov et al. […

Abscopal effect in radioimmunotherapy

M Ashrafizadeh, B Farhood, AE Musa, S Taeb… - International …, 2020 - Elsevier
… For this aim, it is important to induce abscopal effect in primary … is the best choice for inducing
abscopal effect. On the other hand… mechanisms behind abscopal effect by radiotherapy and …

[HTML][HTML] A patient-level data meta-analysis of the abscopal effect

SJ Hatten Jr, EJ Lehrer, J Liao, MS Congzhou… - Advances in Radiation …, 2022 - Elsevier
abscopal effect is defined when a form of local therapy causes tumor regression of both the
target lesion and any untreated tumors. Herein cases of the abscopal effectabscopal effect is …

True abscopal effect in a patient with metastatic non-small cell lung cancer

O Vilinovszki, N Andratschke, M Huellner… - Radiation …, 2021 - Springer
… between abscopal effect versus sole effect of … of abscopal effects occurring after sole
radiotherapy remain extremely rare [2,3,4, 7]. Here, we describe a seldom case of abscopal effect

Abscopal Effect on Bone Metastases from Solid Tumors: A Systematic Review and Retrospective Analysis of Challenge within a Challenge

M Tomaciello, M Conte, FR Montinaro, A Sabatini… - Biomedicines, 2023 - mdpi.com
… The abscopal effect after the irradiation of BMs represents a real phenomenon, already
documented and further studied in our experience. The evidence currently present in the …

Valproic acid triggers radiation-induced abscopal effect by modulating the unirradiated tumor immune microenvironment in a rat model of breast cancer

L Jin, W Duan, Z Cai, D Lim… - Journal of Radiation …, 2021 - academic.oup.com
abscopal effect occurs when localized radiotherapy causes the regression of tumors distant
from the irradiated site. However, such a clinically detectable abscopal effectabscopal effect. …

[HTML][HTML] Radiation Induced Abscopal Effect in a Patient With Malignant Pleural Mesothelioma on Pembrolizumab

R Rittberg, E Chan, S Yip, D Alex, C Ho - Cureus, 2022 - ncbi.nlm.nih.gov
effect. This phenomenon has been reported in cancer patients receiving immune checkpoint
inhibitors (ICI). Here we report a case of presumed abscopal effect in … to the abscopal effect. …

Microwave ablation induces abscopal effect via enhanced systemic antitumor immunity in colorectal cancer

L Yu, H Xie, L Wang, M Cheng, J Liu, J Xu, Z Wei… - Frontiers in …, 2023 - frontiersin.org
… In clinical work, our team discovered that the abscopal effect occurred in a patient with …
stimulated the perfect abscopal effect (15). We also observed an abscopal effect in another case …

Abscopal Effect: An Old Concept with a New Horizon.

AN Abbasi, HK AM, MA Mansha, F Shaukat… - The Gulf Journal of …, 2021 - europepmc.org
Abscopal effect is defined as a phenomenon where radiation delivery at one site induces
shrinkage of disease at a distant site, outside the radiation field. Although it is an old concept …

History and current perspectives on the biological effects of high-dose spatial fractionation and high dose-rate approaches: GRID, Microbeam & FLASH radiotherapy

RJ Griffin, KM Prise, SJ McMahon… - The British journal of …, 2020 - academic.oup.com
abscopal effects as potential mediators of response to GRID. The first introduction to the
concept of abscopal effects … observations of the abscopal effect both experimentally and in the …