Atomic force microscopy of proteinprotein interactions

X Zhang, F Rico, AJ Xu, VT Moy - Handbook of Single-Molecule …, 2009 - Springer
interactions in real time (1,2). This chapter focuses mainly on the application of the … force
microscope (AFM) (3,4), a widely used single-molecule tool, to the study of protein interactions

Measurements of the forces in protein interactions with atomic force microscopy

S Lin, JL Chen, LS Huang, HW Lin - Current Proteomics, 2005 - ingentaconnect.com
… the nonspecific forces that jointly control protein interactions. … The forces acting on the tip
vary, depending on the mode of … of forces likely to be encountered in protein interactions will …

Visualization of a protein-protein interaction at a single-molecule level by atomic force microscopy

K Bonazza, H Rottensteiner, BK Seyfried… - Analytical and …, 2014 - Springer
… indicate that proteins can maintain their reactivity for subsequent interactions with other …
a new analytical perspective for studying protein-protein interactions as it circumvents some …

Chip‐based proteinprotein interaction studied by atomic force microscopy

FS Kao, W Ger, YR Pan, HC Yu… - Biotechnology and …, 2012 - Wiley Online Library
… of protein-to-protein interactions before and after the introduction of a drug candidate is
developed using atomic force microscopy (… in unbinding force between these two proteins before …

Direct visualization of ligand‐protein interactions using atomic force microscopy

CS Neish, IL Martin, RM Henderson… - British journal of …, 2002 - Wiley Online Library
… We have used atomic force microscopy (AFM) to visualize this ligand-protein interaction
this possibility, we examined the interaction between a biotinylated target protein, the enzyme β-…

Specific aptamer− protein interaction studied by atomic force microscopy

Y Jiang, C Zhu, L Ling, L Wan, X Fang… - Analytical …, 2003 - ACS Publications
… in protein detection and new drug development. In this study, the specific interaction between
the protein … measured directly by atomic force microscopy. The single-molecule unbinding …

Unraveling lipid/protein interaction in model lipid bilayers by atomic force microscopy

A Alessandrini, P Facci - Journal of Molecular Recognition, 2011 - Wiley Online Library
… the study of lipid–protein interactions. The research field of lipid–protein interactions includes
the relations between transmembrane proteins and lipids, the interactions of a lipid bilayer …

[HTML][HTML] Atomic force microscopy: a multifaceted tool to study membrane proteins and their interactions with ligands

AM Whited, PSH Park - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
… critical molecular interactions that … force microscopy technique and discuss its application
in the study of a variety of questions related to the interaction between a membrane protein and …

Atomic force microscopy and analytical ultracentrifugation for probing nanomaterial protein interactions

J Schaefer, C Schulze, EEJ Marxer, UF Schaefer… - ACS …, 2012 - ACS Publications
… Adsorption of serum proteins and bovine serum albumin (BSA) was quantified by SDS-…
atomic force microscopy (AFM) and analytical ultracentrifugation (AUC). The protein adsorption to …

Visualizing protein-nucleic acid interactions on a large scale with the scanning force microscope

C Bustamante, C Rivetti - Annual review of biophysics and …, 1996 - annualreviews.org
… Thus, although theories of image formation for probe microscopy exist (9, 33, 56), there is
no general definition of resolution in force microscopy. The most important instrument …