… occurrence of de novo methylation of foreign DNA in mammalian cells. We have now
demonstrated that the de novo methylation of foreign (adenovirus) DNA is initiated at sequences …

… BecauseIL-10 and Igf2r are located on different mouse chromosomes, we reason that at least
one of the genes with altered DNA methylation is located in trans to the transgene insertion …

… We propose that hyper or nearly completely 5′ CG 3′ methylated foreign DNA sequences
would be more stably integrated than less completely methylated foreign genomes. …

… of DNA methylation patterns in the recipient genome at and remote from the site of foreign
DNA … We concluded that the trans-effect of foreign DNA insertion on cellular DNA methylation …

… of DNA methylation … foreign DNA was unmethylated, we questioned whether this was unique
to the HSV and plasmid DNAs used in the study. These vectors are not naturally methylated …

… the changes in DNA methylation of cellular DNA segments in Ad12-transformed cells is very
likely, we have now investigated whether the integration of foreign DNA into the established …

… ' reporter genes driven by aleurone tissue-specific promoters to test the effect of methylation
of foreign DNA on its stability after introduction into barley plants. The foreign DNA was …

… methylation … DNA methylation in tumour cells, particularly in adenovirus type 12 (AdI2)-induced
hamster tumour cells. It is not known whether these changes in cellular DNA methylation …

… global mechanisms of gene regulation, DNA methylation and histone … foreign DNA and
transgenic organisms, the newly integrated foreign DNA frequently becomes de novo methylated…

… Since cell lines propagated in culture and adenovirus genomes as foreign DNA in … analyzed
patterns of DNA methylation in a number of endogenous human gene or DNA segments in …