Physiological evidence that theinterphase'in the formalin test is due to active inhibition
JL Henry, K Yashpal, GM Pitcher, TJ Coderre - Pain, 1999 - Elsevier
… the interphase period in the formalin test is due to active inhibition. Furthermore, the inhibition
which we are reporting here is independent of the concentration of formalin used, and thus …
which we are reporting here is independent of the concentration of formalin used, and thus …
The interphase of the formalin test
… The authors suggested the existence of a single prolonged phase of activation, intersected
by a shorter phase of active inhibition, rather than 2 phases of activation. The aim of the …
by a shorter phase of active inhibition, rather than 2 phases of activation. The aim of the …
The formalin test: characteristics and usefulness of the model
J Sawynok, XJ Liu - Reviews in analgesia, 2003 - ingentaconnect.com
… In rats, formalin generates … active phases involve ongoing peripheral afferent neural activity;
inflammation contributes to phase 2 activity and the interphase results from active inhibition. …
inflammation contributes to phase 2 activity and the interphase results from active inhibition. …
The formalin test in the mouse: a parametric analysis of scoring properties
GM Saddi, FV Abbott - Pain, 2000 - Elsevier
… formalin test using the time-sampling method recently developed for infant and adult rats.
Formalin … log formalin concentration–effect curves was 3–4% in both phases. Habituation to the …
Formalin … log formalin concentration–effect curves was 3–4% in both phases. Habituation to the …
Comparison of the antinociceptive effect of celecoxib, diclofenac and resveratrol in the formalin test
… (this study), were active in the formalin test are in line with … inhibitor resveratrol and the
non-selective COX inhibitor diclofenac produced peripheral antinociception in the rat formalin test…
non-selective COX inhibitor diclofenac produced peripheral antinociception in the rat formalin test…
Activity‐Guided Isolation of Bioactive Constituents with Antinociceptive Activity from Muntingia calabura L. Leaves Using the Formalin Test
MI Mohamad Yusof, MZ Salleh… - Evidence‐Based …, 2013 - Wiley Online Library
… Based on our findings, the MEMC inhibited the early and late phases of formalin test as
reported by Sani et al. [12]. This finding leads us to partition the MEMC into PEP, EAP, and AQP …
reported by Sani et al. [12]. This finding leads us to partition the MEMC into PEP, EAP, and AQP …
Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat.
AB Malmberg, TL Yaksh - Journal of Pharmacology and Experimental …, 1992 - ASPET
… in 50% inhibition of the formalin control response. b Potency ratio showing the relative potency
… 24 hr before and 9 mm after formalin. P < .05 as compared to the inhibition of the flinching …
… 24 hr before and 9 mm after formalin. P < .05 as compared to the inhibition of the flinching …
Evaluation of the tail formalin test in mice as a new model to assess local analgesic effects
Y Kolesnikov, M Cristea, G Oksman, A Torosjan… - Brain research, 2004 - Elsevier
… inhibited formalin-induced pain on 27% and 7%, respectively (Fig. 5A and B). However,
when the same doses were administered together, the combination inhibited the formalin-…
when the same doses were administered together, the combination inhibited the formalin-…
Evaluation of the antinociceptive activities of enaminone compounds on the formalin and hot plate tests in mice
W Masocha, SB Kombian, IO Edafiogho - Scientific Reports, 2016 - nature.com
… inhibitors, which inhibit both phases of the formalin test 29 , but not indomethacin, which
inhibits only the inflammatory phase 26 . The chemical structure of E139 and E138 has the …
inhibits only the inflammatory phase 26 . The chemical structure of E139 and E138 has the …
The formalin test: a dose–response analysis at three developmental stages
CJ Teng, FV Abbott - Pain, 1998 - Elsevier
… formalin concentrations. Flexion, shaking and licking the injected limb and hind-limb kicking
correlated strongly with log formalin … at the highest formalin concentration tested. Flexion, …
correlated strongly with log formalin … at the highest formalin concentration tested. Flexion, …
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