Phenotypic heterogeneity of monogenic frontotemporal dementia

A Benussi, A Padovani, B Borroni - Frontiers in aging neuroscience, 2015 - frontiersin.org
Frontotemporal dementia (FTD) is a genetically and pathologically heterogeneous disorder
characterized by personality changes, language impairment, and deficits of executive …

Neurochemical features of frontotemporal dementia

AW Procter, M Qurne, PT Francis - Dementia and geriatric cognitive …, 1999 - karger.com
… with frontotemporal dementia (FTD) including 10 subjects with Pick pathology and 6 with
dementia … In both forms of FTD there was not evidence of any cholinergic abnormality, unlike the …

Frontotemporal dementia: a bridge between dementia and neuromuscular disease

ASL Ng, R Rademakers… - Annals of the New York …, 2015 - Wiley Online Library
The concept that frontotemporal dementia (FTD) is a purely cortical dementia has largely
been refuted by the recognition of its close association with motor neuron disease, and the …

Frontotemporal dementia

N Graff-Radford, B Woodruff - CONTINUUM: Lifelong Learning in …, 2004 - journals.lww.com
… include tau inclusions, ubiquitin inclusions, and dementia lacking distinctive histology. The
majority of genetically characterized forms of familial FTD involve mutations in the microtubule…

Frontotemporal dementia: correlations between psychiatric symptoms and pathology

M Scarioni, P Gami‐Patel, Y Timar… - Annals of …, 2020 - Wiley Online Library
… FTLD and form an … frontotemporal dementia should include the presence and nature of
neuropsychiatric symptoms. ANN NEUROL 2020;87:950–961 The term frontotemporal dementia (…

Right temporal variant frontotemporal dementia is pathologically heterogeneous: a case-series and a systematic review

H Ulugut, AA Dijkstra, M Scarioni… - Acta neuropathologica …, 2021 - Springer
… the diverse pathologies of the right and left temporal variants of frontotemporal dementia. …
Frontotemporal dementia (FTD) is a neurodegenerative disorder that predominantly affects the …

The molecular basis of frontotemporal dementia

M Neumann, M Tolnay, IRA Mackenzie - Expert reviews in molecular …, 2009 - cambridge.org
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular basis.
Familial FTD has been linked to mutations in several genes, including those encoding the …

Distinctive neuropsychological patterns in frontotemporal dementia, semantic dementia, and Alzheimer disease

JH Kramer, J Jurik, JS Sharon, KP Rankin… - Cognitive and …, 2003 - journals.lww.com
… semantic dementia groups were significantly impaired relative to the frontotemporal dementia
Frontotemporal dementia patients performed significantly worse on backward digit span …

Frontotemporal dementia with tau pathology

L Gasparini, B Terni, MG Spillantini - Neurodegenerative diseases, 2007 - karger.com
… -17 the gene that is mutated is also that to encode the protein that forms the inclusions. …
tau gene in cases with familial frontotemporal dementia and parkinsonism linked to chromosome …

The frontotemporal dementia-motor neuron disease continuum

JR Burrell, GM Halliday, JJ Kril, LM Ittner, J Götz… - The Lancet, 2016 - thelancet.com
… We now know that frontotemporal dementia-motor neuron disease—ie, where both frontotemporal
dementia and motor neuron disease are present—is an important dementia syndrome …