… -skill learning in mutants. Our results indicate that FOXP2 is critical for the function of striatal
… in vivo, which are important not only for speech but also for other striatal-dependent skills. …

… skill learning, auditory-motor association learning is impaired by these heterozygous Foxp2
mutations, … we demonstrate that the strength of the effect depends on the type of the mutation. …

… -skill learning [7]. Against this background, it is valuable to investigate roles of genes like
FOXP2 by … (Grey box) This line has a missense mutation in exon 14 of the Foxp2 gene; one of 3 …

… series, our heterozygous Foxp2 mutants are fully viable … -skill learning and functional
properties of relevant circuits in mice carrying Foxp2 disruptions and focuses on a point mutation …

… Additionally, evidence from in vivo recordings shows that Foxp2 mutant mice display …
inhibition partially rescues the motor skill learning deficits observed in heterozygous Foxp2 …

… skill learning, given that mice lacking one functional allele of murine Foxp2 are reported to
exhibit learning … 1B), and we tested acquisition in new, naïve cohorts of mutant and WT mice. …

… Rare mutations of the FOXP2 transcription factor gene cause a … FoxP2 dosage yields
abnormal synaptic plasticity and impaired motor-skill learning in mice, and disrupts vocal learning …

… learning may share homologous aspects with vocal learning using the dFoxP gene. Our
evidence suggests that the Drosophila FoxP2 … /or motor skill deficits in patients with mutations in …

… and molecular experiments to perform in vivo interventions aimed at amelioration of the
motor skill learning deficits present in mice with heterozygous Foxp2 mutations. …

… opposed to genetic mutation, across FOXP2 may be involved … FoxP2 between song-learning
birds and non-song-learning … deficits in motor-skill learning, rather than gross motor skills as …