Adherence to clotting factors among persons with hemophilia A or B

EP Armstrong, DC Malone, S Krishnan, MJ Wessler - Hematology, 2015 - Taylor & Francis
patients with severe hemophilia and estimated that patients … measure adherence in severe
hemophilia patients. A ratio was … Frequency of factor administration was not available from the …

Bleeding in carriers of hemophilia

I Plug, EP Mauser-Bunschoten… - Blood, 2006 - ashpublications.org
… little influence on the reported frequency of bleeding. A more serious problem is that women
who grew up in families with hemophilia patients may judge bleeding symptoms differently …

[HTML][HTML] Rate of inhibitor development in previously untreated hemophilia A patients treated with plasma‐derived or recombinant factor VIII concentrates: a systematic …

A Iorio, S Halimeh, S Holzhauer, N Goldenberg… - Journal of Thrombosis …, 2010 - Elsevier
estimate the cumulative incidence and prevalence of inhibitors in various HA populations, this
review was specifically focused on estimating … that variables such as frequency of inhibitor …

Cost of care and quality of life for patients with hemophilia complicated by inhibitors: the COCIS Study Group

A Gringeri, LG Mantovani, L Scalone, PM Mannucci… - Blood, 2003 - ashpublications.org
frequency of events was lower than that reported in other cohorts of patients with hemophilia
… The overall prevalence of inhibitors in patients with hemophilia A or B is estimated to be …

[HTML][HTML] In silico evaluation of limited blood sampling strategies for individualized recombinant factor IX prophylaxis in hemophilia B patients

T Preijers, H Hazendonk, K Fijnvandraat… - Journal of Thrombosis …, 2017 - Elsevier
… Challenges in constructing such schemes concern the balance between sufficient information
to estimate a subject's PK parameters and the frequency of blood sampling imposed on a …

Modeling to predict factor VIII levels associated with zero bleeds in patients with severe hemophilia A initiated on tertiary prophylaxis

P Chowdary, K Fischer, PW Collins… - Thrombosis and …, 2020 - thieme-connect.com
estimated from single-dose individual pharmacokinetics. The highest estimated FVIII level at
which patients … one considers that frequency and adherence to frequency have the greatest …

[HTML][HTML] Hemophilia B: characterization of genetic variants and detection of carriers

CK Kasper, B Østerud, JY Minami, W Shonick… - Blood, 1977 - Elsevier
… Probability curves were derived to estimate the chance of a woman being a hemophilia B …
one hemophilic patient fell into one of the above groups and a second hemophilic patient

Costs and utilization of hemophilia A and B patients with and without inhibitors

EP Armstrong, DC Malone, S Krishnan… - Journal of medical …, 2014 - Taylor & Francis
… The third limitation is that this study may have under-estimated the number of patients with …
the frequency of inhibitors within the hemophilia cohort was low, there was a higher frequency

[HTML][HTML] Break‐through bleeding in relation to predicted factor VIII levels in patients receiving prophylactic treatment for severe hemophilia A

PW Collins, VS Blanchette, K Fischer… - Journal of Thrombosis …, 2009 - Elsevier
… In order to estimate the … frequency of the prophylactic regimen, in the 1–6 year olds (coefficient
–0.0348, median 89% adherence to frequency and 3.1 annual bleed rate), if the patients

The bleeding phenotype in people with nonsevere hemophilia

FR Kloosterman, AF Zwagemaker, CN Bagot… - Blood …, 2022 - ashpublications.org
… , frequency, and severity of bleeding in nonsevere hemophilia is … phenotype may provide
more robust estimates. Moreover, research … Patient characteristics are presented in Table 1. …