… estimation. This paper reports a one-stage method for a population pharmacokinetic study of
factor VIII. The Bayesian estimation … factor VIII dosage in hemophilic patients before surgery. …

… ,[1] [2] with a frequency of hemophilia A estimated at 11 cases per 100,000 men, four times
… in the Netherlands in 283 severe hemophilia patients (252 with hemophilia A and 30 with …

… of bleeds” by both hemophilia patients and their parents, as … of hemophilia is perceived as
very costly, with an estimated … , as well as frequency of visits to medical professionals due to …

… inhibitors, estimating the burden of transfusion related complications at our hemophilia care
… CONCLUSION: It is the frequency & persistence of blood loss together with minimal trauma, …

… Patients value low frequency of bleeding per year and low risk of development of inhibitors
the most. An increase of risk and frequency … The World Federation of Hemophilia estimates …

… Therefore, data of hemophilia patients in this province provide us with a valuable estimate
for the whole country. Prevalence in this province is 14 per 100 000 and 2.5 per 100 000 …

… in our survey of 240 patients with hemophilia A, we estimate the … We believe that this estimate
is quite conservative. For … , the expected frequency of C-to-T mutations in these patients is 7/…

… skinfolds and the estimated percent fat were significantly higher in the hemophilia patients
(H) … The effect of resistance exercise on the frequency of bleeding in the hemophilic patient. …

… Eleven of the above studies examined whether there were one or more reported hemophilic
patients among the families analyzed, to estimate sporadic case frequency. A study on …

… Federation of Hemophilia (WFH) estimated that there are approximately 30,000 people with
… This high frequency of injections is a burden to patients, especially those of pediatric age, …