… activities according to expected frequency and severity of … This study provides estimates
of the risk of bleeding … Such bleeds occurred most often in patients who frequently bleed…

… could be used to identify hemophilia patients with short half-life… that all patients have the
infusion frequency they desire or to … estimate the trough we would obtain by switching the patient …

… patient’s rAHF-PFM PK (infusion interval, estimated t 1/2 , … PK and bleeding frequency at
the individual patient level, we … HRQOL scores of patients with hemophilia A were lower than …

… clinical observation that patients with moderate hemophilia (ie, … First, we provide both average
estimates as well as their … effect of changing dose and frequency on future plasma levels …

… We have developed a method to estimate the sex ratio of the mutation frequencies… estimate
of the reproductive fitness of haemophilia patients and carriers. Information from 462 patients …

… population of hemophilia B patients. Statistical data on the hemophilia patients registered in
… affected son, and the estimated frequency of carriers of a new hemophilia B mutation in the …

… dosing frequency, and factor consumption in patients treated … products, and dosing
frequency and factor consumption were … real-world data for patients with hemophilia A receiving …

… further improve accuracy of PK profile estimates for an individual patient but from a resource
… , as well as the reduced bleed frequency in patients with severe haemophilia B compared to …

… use of PopPK for profiling patients with hemophilia A receiving … eventually affected their
subsequent bleeding frequencies. … PK profiles were estimated using myPKFiT® for patients on …

… common among patients with hemophilia. This systematic review aimed to obtain more
precise estimates of ICH incidence and mortality in hemophilia, which may be important for …