… Frontotemporal dementia ( FTD ) is a clinical syndrome with a … Understanding the associated
pathogenic mechanisms and … This article is part of the Frontotemporal Dementia special …

… of neuroinflammatory mechanisms in FTD and describes how advances in our understanding
of these mechanisms, in FTD as well as in other neurodegenerative diseases, might …

… genetically mediated forms of frontotemporal dementia have spearheaded this enterprise. …
of the frontotemporal dementias, motivated by our emerging understanding of the mechanisms …

… disease mechanism in FTLD which could affect TDP-43-, FUS-, and C9orf72-dependent
disease … to drive their propagation in a prionlike mechanism. However, to allow propagation of …

Frontotemporal dementia (FTD) is a neurodegenerative disorder predominantly affecting
the frontal and temporal lobes. Genome-wide association studies (GWAS) on FTD identified …

… Frontotemporal dementia (… disease mechanism in FTD and ALS. Further studies into the
normal function of many of these proteins are required and will help uncover the mechanisms …

… loss-of-function disease mechanism, the accumulation of … RNA gain-of-function disease
mechanism. On the basis of current … of each disease mechanism to neurodegeneration and TDP-…

… This is the case for early frontotemporal dementia (FTD) and bipolar disorder. In its initial
stages, FTD is characterized by behavioral or language disturbances in the absence of …

… pathophysiological mechanisms in frontotemporal dementia (… used for clinical screening of
disease-influenced CSF proteins … of disease-influenced CSF proteins in Alzheimer’s disease (…

… which led to the use of Pick's disease as a synonym for frontotemporal dementia. In 1982,
Mesulam described a language subtype of the disorder, later defined as primary progressive …