[HTML][HTML] Degradation of cognitive timing mechanisms in behavioural variant frontotemporal dementia

SMD Henley, LE Downey, JM Nicholas, KM Kinnunen… - Neuropsychologia, 2014 - Elsevier
… The current study examined motor timing in frontotemporal dementia (FTD), which
manifests as progressive deterioration in social, behavioural and cognitive functions. Twenty-patients …

Frontotemporal dementia: a bridge between dementia and neuromuscular disease

ASL Ng, R Rademakers… - Annals of the New York …, 2015 - Wiley Online Library
… with Paget's disease of bone and frontotemporal dementia (… subtypes linked to neuromuscular
disease and discuss the … levels or by other mechanisms remains to be determined. …

Astrocytic degeneration relates to the severity of disease in frontotemporal dementia

M Broe, J Kril, GM Halliday - Brain, 2004 - academic.oup.com
… In this study we tested this hypothesis by analysing a common cell death mechanism, …
different disease stages in different subtypes of FTD may identify a common disease mechanism. …

Lysosomal dysfunction at the centre of Parkinson's disease and frontotemporal dementia/amyotrophic lateral sclerosis

RL Wallings, SW Humble, ME Ward… - Trends in …, 2019 - cell.com
… in these diseases and discuss recent evidence for converging mechanisms. This review …
to argue that lysosomal failure is a primary mechanism of disease, rather than merely reflecting …

Frontotemporal dementia—a brief review

M Sjögren, C Andersen - Mechanisms of ageing and development, 2006 - Elsevier
dementia and the forth most common type of senile dementia, … such as Pick's disease,
frontotemporal lobar degeneration, … palsy, and frontotemporal dementia with parkinsonism linked …

[HTML][HTML] The development of C9orf72-related amyotrophic lateral sclerosis and frontotemporal dementia disorders

Q Yang, B Jiao, L Shen - Frontiers in genetics, 2020 - frontiersin.org
… (ALS) and frontotemporal dementia (FTD). There are three main disease mechanisms: loss
of … While many of the downstream mechanisms have been identified, the specific pathogenic …

[HTML][HTML] An update on genetic frontotemporal dementia

CV Greaves, JD Rohrer - Journal of neurology, 2019 - Springer
… or provision of appropriate psychological support mechanisms for those living through the
at-risk phase. This will become even more relevant as disease-modifying therapy trials start in …

Frontotemporal dementia caused by CHMP2B mutations

AM Isaacs, P Johannsen, I Holm… - Current Alzheimer …, 2011 - ingentaconnect.com
… prion diseases [53-57], and deletion of key autophagy genes leads to neurodegeneration in
mice [58, 59]. Deciphering the precise mechanism … neurodegenerative disease mechanisms. …

Mouse models of frontotemporal dementia

ED Roberson - Annals of neurology, 2012 - Wiley Online Library
… using them to determine mechanisms by which TDP-43 contributes to the disease. One of …
(see Table 2), suggesting that other mechanisms may be more pertinent. Because of the tight …

[HTML][HTML] Frontotemporal dementia, where do we stand? A narrative review

A Antonioni, EM Raho, P Lopriore, AP Pace… - International journal of …, 2023 - mdpi.com
… Following the description of the molecular genetics of the three most common genetic
causes, we will trace an overview of the key pathological mechanisms involved in FTD …